全身肝素化在脑血管造影术中的应用研究进展  

Research progress on periprocedural intravenous heparin applying in digital subtraction angiography

作　　者：王征[1] 罗继昌 封一定 覃勤朴 Wang Zheng;Luo Jichang;Feng Yiding;Qin Qinpu(Department of Interventional Neuroradiology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院介入放射科,北京100053 [2]首都医科大学宣武医院神经外科,北京100053

出　　处：《中国脑血管病杂志》2021年第10期728-732,共5页Chinese Journal of Cerebrovascular Diseases

基　　金：首都医科大学宣武医院院级专项课题(XWHL-2018010)。

摘　　要：目前大多数脑血管造影术中仍静脉使用肝素进行术中抗凝,但参考小剂量甚至无肝素化冠状动脉造影术的良好结局,并且考虑到自发性出血和肝素诱发的血小板减少症等不良反应,脑血管造影术中的全身肝素化是否必要,仍具争议。该文通过回顾脑血管造影术中肝素使用的相关研究,旨在阐述目前全身肝素化在脑血管造影术中存在的争议,并对未来脑血管造影术中减少肝素使用剂量的可能性进行展望。At present,periprocedural intravenous heparin is widely used during digital subtraction angiography.However,considering the good outcome of coronary angiography with low-dose or without heparin as well as the risk of spontaneous hemorrhage and heparin-induced thrombocytopenia,it is still controversial whether to use heparin or not in routine angiography.The authors reviewed the studies of heparin usage during angiography,aiming to discuss the current controversy of systemic heparinization in cerebral angiography and to forecast the possibility of reducing the dose of heparin in the future.

关 键 词：脑血管造影 肝素 凝血 综述 

分 类 号：R743[医药卫生—神经病学与精神病学]