周围性听觉障碍与阿尔茨海默病的关系  

Association of peripheral hearing loss and Alzheimer's disease

作　　者：李丹凝 张巍[2] LI Dan-Ning;ZHANG Wei(Center for Neurology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Department of Cognitive Disorders,Center for Neurology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院神经病学中心,北京100070 [2]首都医科大学附属北京天坛医院神经病学中心认知障碍性疾病科,北京100070

出　　处：《中华老年多器官疾病杂志》2021年第10期784-788,共5页Chinese Journal of Multiple Organ Diseases in the Elderly

基　　金：国家自然科学基金面上项目(81970992,81571229,81071015,30770745);国家重点研发计划(2016YFC1306300,2016YFC1306000);国家重点研发计划-欧盟地平线2020计划合作项目(2017YFE0118800-779238);北京市教育委员会科技发展计划重点项目(KZ201610025030);北京市自然科学基金重点项目(4161004);北京市自然科学基金面上项目(7082032);北京市中医药科技发展资金项目(JJ2018-48)。

摘　　要：周围性听觉障碍是好发于老年群体的感官障碍,阿尔茨海默病(AD)是患病率最高的神经系统变性疾病,研究发现周围性听觉障碍是AD发生的独立危险因素。目前两者相关的机制假说包括认知储备机制、社会隔离机制及共同病因机制。干预周围性听觉障碍可以延缓老年人认知功能减退,改善AD患者情绪及行为症状。Peripheral hearing loss is quite prevalent in senior population,while Alzheimer's disease(AD)is the most frequent neurodegenerative disease.Evidence showed that peripheral hearing loss is an independent risk factor of AD.The hypotheses regarding the mechanism of their relationship include cognitive reserve,social isolation and common etiology.Intervention of peripheral hearing loss attenuates the cognitive decline of senior population,and improves emotional and behavioral symptoms of AD patients.

关 键 词：阿尔茨海默病 周围性听觉障碍 老化 助听器 

分 类 号：R749.16[医药卫生—神经病学与精神病学]