仿多巴化合物在牙本质-树脂粘接中应用的研究进展  

Research progress in the application of dopa-inspired compounds to improve the dentin-resin bonding

作　　者：闫琳琳 张志民[1] 赵远航 赵红 邹馨颖 宋嘉卓 刘新 张红[1] Yan Linlin;Zhang Zhimin;Zhao Yuanhang;Zhao Hong;Zou Xinying;Song Jiazhuo;Liu Xin;Zhang Hong(Department of Endodontics,Hospital of Stomatology,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学口腔医院牙体牙髓病科,长春130021

出　　处：《中华口腔医学杂志》2021年第10期1040-1044,共5页Chinese Journal of Stomatology

基　　金：吉林省发展和改革委员会2020年省预算内基本建设资金(2020C029-2)。

摘　　要：多巴是贻贝足丝蛋白的主要成分,其可通过形成双氢键、π-π/π-阳离子键以及螯合金属促进贻贝在固体物质表面产生较牢固的黏附。因此,将仿多巴化合物应用于牙本质-树脂粘接领域有广阔的前景。本文综述贻贝足丝蛋白的黏附机制以及仿多巴化合物在牙本质-树脂粘接领域的应用,以期为牙本质-树脂粘接的优化研究提供参考。Mussle foot protein has a main component which is named dopa.Dopa can be used to promote a relatively firm adhesion of mussels to the surface of solid materials through forming dihydrogen bonds,π-π/π-cation bonds and chelating metals,etc.To exploit these interactions,there is the opportunity to apply dopa-inspired compounds to improve the dentin-resin bonding.The current review provides valuable information concerning the mechanism of adhesion mediated by mussel foot protein and describes the application of dopa-inspired compounds in the dentin-resin bonding.The article provides novel information for future research in optimization of the properties of dentin-resin bonding.

关 键 词：多巴胺 牙本质粘结剂 牙科材料 牙粘合 多巴 仿多巴化合物 

分 类 号：R783.1[医药卫生—口腔医学]