Contemporary Approaches toα,β-Dehydroamino Acid Chemical Modifications  

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作  者:ZHANG Mengqian HE Peiyang LI Yanmei 

机构地区:[1]Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology,Department of Chemistry,Tsinghua University,Beijing,100084,P.R.China [2]Beijing Institute for Brain Disorders,Beijing,100069,P.R.China [3]Center for Synthetic and Systems Biology,Tsinghua University,Beijing,100084,P.R.China

出  处:《Chemical Research in Chinese Universities》2021年第5期1044-1054,共11页高等学校化学研究(英文版)

基  金:This work was supported by the National Key R&D Program of China(Nos.2018YFA0507600,2019YFA0904200);the National Natural Science Foundation of China(No.92053108).

摘  要:As one of the most common unnatural amino acids(uAAs),α,β-dehydroamino acids(α,β-dhAAs)can be found in various ribosomally synthesized and post-translationally modified peptides(RiPPs)and other naturally occurring peptides.In recent years,novel reactions forα,β-dhAA modification continue to emerge.Due to their unique electrophilicity different from 20 natural amino acids,α,β-dhAAs.

关 键 词:TRANSLATIONAL CONTINUE ACIDS 

分 类 号:O62[理学—有机化学]

 

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