Design and Synthesis of Sulfanilamide Aminophosphonates as Novel Antibacterial Agents towards Escherichia coli  

作　　者：Juan Wang Mohammad Fawad Ansari Jian-Mei Lin Cheng-He Zhou 

机构地区：[1]Institute of Bioorganic&Medicinal Chemistry,Key Laboratory of Luminescence Analysis and Molecular Sensing(Southwest University),Ministry of Education,School of Chemistry and Chemical Engineering,Southwest University,Chongqing 400715,China [2]School of Medicine,University of Electronic Science and Technology of China,Chengdu,Sichuan 610072,China

出　　处：《Chinese Journal of Chemistry》2021年第8期2251-2263,共13页中国化学（英文版）

基　　金：This research was supported in part by grants from the National Natural Science Foundation of China(No.21971212);the Postdoctoral Science Foundation Project of Chongqing Science and Technology Bureau(No.cstc2019jcyj-bshX0124);the China Postdoctoral Science Foundation(No.2019M653821XB);the Chongqing Special Foundation for Postdoctoral Research Proposal(No.XmT2018082).

摘　　要：The limit ability of traditional antibiotics to treat drug resistant bacteria calls for new therapeutic alter natives.A class of unique sul-fanilamide aminophosphonates as new potential agents against microbes was synthesized by one-pot three-component reaction.

关 键 词：SULFONAMIDES AMINOPHOSPHONATE IMIDAZOLE Membranes DNA 

分 类 号：O62[理学—有机化学]