AMINOPHOSPHONATE

作品数：7被引量：8H指数：2
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相关期刊：《有机化学》《Chinese Journal of Catalysis》《Chinese Journal of Chemistry》《Chinese Chemical Letters》更多>>
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Recent Advances on the Synthesis and Application ofα,α-Difluoro-β-aminophosphonates
《有机化学》2024年第12期3686-3701,共16页Du Youlong Wang Qian Mei Haiboa Pajkert Roman Röschenthaler Gerd-Volker Han Jianlin 
国家自然科学基金(No.21761132021)资助项目.
α,α-Difluoro-β-aminophosphonates can be looked as structural analogies withα-amino acids,which have attracted great attention in biological and medicinal chemistry during the past decades.Furthermore,these compoun...
关键词：AMINOPHOSPHONATE α α-difluoro-β-aminophosphonate CARBENE diazo compound AMINE bioactive compound 
Design and Synthesis of Sulfanilamide Aminophosphonates as Novel Antibacterial Agents towards Escherichia coli被引量：3
《Chinese Journal of Chemistry》2021年第8期2251-2263,共13页Juan Wang Mohammad Fawad Ansari Jian-Mei Lin Cheng-He Zhou 
This research was supported in part by grants from the National Natural Science Foundation of China(No.21971212);the Postdoctoral Science Foundation Project of Chongqing Science and Technology Bureau(No.cstc2019jcyj-bshX0124);the China Postdoctoral Science Foundation(No.2019M653821XB);the Chongqing Special Foundation for Postdoctoral Research Proposal(No.XmT2018082).
The limit ability of traditional antibiotics to treat drug resistant bacteria calls for new therapeutic alter natives.A class of unique sul-fanilamide aminophosphonates as new potential agents against microbes was syn...
关键词：SULFONAMIDES AMINOPHOSPHONATE IMIDAZOLE Membranes DNA 
Enantioselective synthesis of quaternary α-aminophosphonates by organocatalytic Friedel–Crafts reactions of indoles with cyclicα-ketiminophosphonates被引量：1
《Chinese Journal of Catalysis》2017年第5期784-792,共9页Zhong Yan Xiang Gao Yong‐Gui Zhou 
supported by the National Natural Science Foundation of China(21532006,21690074)~~
An efficient asymmetric Friedel-Crafts reaction has been developed for the synthesis of optically active quaternaryα‐aminophosphonates with up to98%ee.The synthesis involves the reaction of cyclicα‐ketiminophospho...
关键词：Friedel–Crafts reaction Quaternary α‐aminophosphonate INDOLE Chiral phosphoric acid 
A General and Highly Selective Method for the Asymmetric Synthesis of Trifluoromethyl-Substituted α- and β-Aminophosphonates
《Chinese Journal of Chemistry》2013年第7期892-900,共9页Lijing Wang Qilong Shen Long Lu 
Acknowledgement The authors gratefully acknowledge the financial support from National Basic Research Program of China （Nos. 2012CB821600, 2010CB126103）, the Key Program of the National Natural Science Foundation of China （No. 21032006）, National Natural Science Foun- dation of China （Nos. 21172244/21172245/B020304）, Agro-scientific Research in the Public Interest （No. 201103007）, the National Key Technologies R＆D Pro- gram （No. 2011BAE06B05）, and Shanghai Scientific Research Program （No. 10XD 1405200）.
A highly selective method for the asymmetric formation of trifluoromethyl-substituted α- and β-aminophos- phonates was described. The reaction proceeded with high yields and good to excellent diastereoselectivity. T...
关键词：TRIFLUOROMETHYL AMINOPHOSPHONATE ASYMMETRIC FLUORINE 
An efficient and green preparation of 5-aminophosphonate substituted pyrimidine nucleosides under solvent-free conditions被引量：1
《Chinese Chemical Letters》2010年第10期1191-1194,共4页Xin Ying Zhang Ying Ying Qu Xue Sen Fan 
National Natural Science Foundation of China(Nos.20772025 and 20972042);the Program for Science & Technology Innovation Talents in Universities of Henan Province(No.2008HASTIT006);Innovation Scientists and Technicians Troop Construction Projects of Henan Province(No.104100510019);the Natural Science Foundation of Henan Province(Nos.092300410192 and 094300510054)
An environmentally benign and highly efficient one-pot preparation of α-aminophosphonates under solvent-free conditions was developed. By employing this method, 5-aminophosphonate substituted pyrimidine nucleosides w...
关键词：AMINOPHOSPHONATE 5-Substituted pyrimidine nucleoside Solvent-free reaction Green synthesis 
The design and synthesis of a novel organophosphorus compound containing the structure of both β-amino acid and β-aminophosphonate
《Chinese Chemical Letters》2010年第7期810-812,共3页Han Bing Teng 
A novel organophosphorus compound containing the structure of bothβ-amino acid andβ-aminophosphonate is designed and synthesized.Arbuzov reaction with P（OEt）_3,the N-Boc protected iodide 3 cannot provide the desir...
关键词：β-Amino acid β-Aminophosphonate Neighboring-group participation Arbuzov reaction Amino-protecting group 
Synthesis and Antifungal Activity of Novel Chiral α-Aminophosphonates Containing Fluorine Moiety被引量：3
《Chinese Journal of Chemistry》2006年第11期1581-1588,共8页杨松 高兴文 刁春玲 宋宝安 金林红 徐广芳 张国平 王伟 胡德禹 薛伟 周霞 卢平 
Project supported by the National Key Program for Basic Research （Nos. 2003CB114404, 2005CCA01500）, the National Natural Science Foundation of China （No. 20362004） and the Doctoral Program Foundation of the Ministry of Education, China （No. 20040657003）.
Chiral α-aminophosphonates were synthesized using （R） or （S）-1-phenylethylamine in the presence of BF3·Et2O under microwave irradiation in moderate to good yields. The new compounds were identified by ^1H NMR, ^...
关键词：chiral aminophosphonate fluorine moiety antifungal activity microwave irradiation SYNTHESIS 
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