歪嘴巴膏翳风穴贴敷治疗急性特发性面神经麻痹临床研究  

Clinical Study on Application of Waizuiba Ointment at Yifeng Point for Acute Idiopathic Facial Palsy

作　　者：鄢琼[1] 李红琴[1] 曹利民[1] 刘海云[1] 杨娜[1] YAN Qiong;LI Hongqin;CAO Limin;LIU Haiyun;YANG Na

机构地区：[1]杭州市萧山区中医院神经内科,浙江杭州311201

出　　处：《新中医》2021年第19期78-82,共5页New Chinese Medicine

基　　金：浙江省中医药科技计划项目(2016ZBl09)。

摘　　要：目的:观察歪嘴巴膏翳风穴贴敷治疗急性特发性面神经麻痹的临床疗效。方法:选取特发性面神经麻痹患者98例,按随机数字表法分为对照组和观察组各49例。对照组给予西医常规治疗,观察组在对照组基础上给予歪嘴巴膏贴敷翳风穴。比较2组临床疗效、治疗前后House-Brackmann (H-B)面神经功能分级、面部残疾指数(FDI)评分、血管内皮祖细胞(EPCs)计数,统计住院时间和费用、肌电图(EMG)恢复正常率及不良反应情况。结果:观察组总有效率为79.59%,高于对照组53.06%,差异有统计学意义(P<0.05)。治疗前,2组H-B分级比较,差异无统计学意义(P>0.05)。治疗后,2组Ⅰ~Ⅱ级率较治疗前升高,观察组Ⅰ~Ⅱ级率高于对照组,差异均有统计学意义(P<0.05)。治疗前,2组躯体功能(FDIP)、社会生活功能(FDIS)评分比较,差异无统计学意义(P>0.05)。治疗后,2组FDIP、FDIS评分较治疗前升高,观察组FDIP、FDIS评分高于对照组(P<0.05)。治疗前,2组EPCs计数、EPCs集落数比较,差异无统计学意义(P>0.05)。治疗后,2组EPCs计数、EPCs集落数较治疗前升高,观察组EPCs计数、EPCs集落数高于对照组(P<0.05)。观察组肌电图恢复正常率为71.43%,高于对照组42.86%,差异有统计学意义(P<0.05)。观察组住院时间、住院费用低于对照组,差异均有统计学意义(P<0.05)。观察组不良反应发生率为10.20%,低于对照组28.57%,差异有统计学意义(P<0.05)。结论:歪嘴巴膏贴敷翳风穴联合西医治疗急性特发性面神经麻痹患者,可更好地改善患者面瘫症状和肌肉功能,增加血管内膜修复能力,缩短住院时间。Objective: To observe the clinical effect of the application of Waizuiba ointment at Yifeng point on treating acute idiopathic facial palsy. Methods:A total of 98 patients with idiopathic facial palsy were selected and divided into the control group and the observation group according to random number table,49 cases in each group. The control group was given conventional western medicine treatment, and the observation group was additionally given Waizuiba ointment at Yifeng point based on the treatment of the control group. The clinical effect,grading of House-Brackmann(H-B) facial nerve function,score of Facial Disability Index(FDI),vascular endothelial progenitor cells(EPCs) before and after treatment were compared between the two groups. The length and cost of hospital stay,rate of electromyography(EMG) back to normal and adverse reactions were counted. Results:The total effective rate was 79.59% in the observation group,higher than that of53.06% in the control group,the difference being significant(P<0.05). Before treatment,there was no significant difference in H-B grading between the two groups(P>0.05). After treatment,the rate of Ⅰto Ⅱ in the two groups was increased when compared with that before treatment,and the above rate in the observation group was higher than that in the control group,differences being significant(P<0.05). Before treatment, there was no significant difference in the PDI of physical function(FDIP) and the FDI of social function(FDIS) scores between the two groups(P>0.05). After treatment,FDIP and FDIS scores in the two groups were increased when compared with those before treatment,and those in the observation group were higher than those in the control group(P<0.05). Before treatment,there was no significant difference in EPCs count and EPCs colony count between the two groups(P>0.05). After treatment,the EPCs count and EPCs colony count in the two groups were increased when compared with those before treatment,and the above indexes in the observation group were higher than thos

关 键 词：急性特发性面神经麻痹 歪嘴巴膏 翳风穴 穴位贴敷 面神经功能 面部残疾指数 血管内皮祖细胞 肌电图 

分 类 号：R745.12[医药卫生—神经病学与精神病学]