抗接触蛋白相关蛋白2抗体脑炎合并可逆性后部脑病综合征一例  

Anti-contactin associated protein-like 2 antibody encephalitis complicated with reversible posterior encephalopathy syndrome:a case report

作　　者：杨继鲜 戴淑娟[1] 赵恒林 张彬阳 艾青龙[1] 钟莲梅[1] Yang Jixian;Dai Shujuan;Zhao Henglin;Zhang Binyang;Ai Qinglong;Zhong Lianmei(Department of Neurology,the First Affiliated Hospital of Kunming Medical University,Kunming 650032,China)

机构地区：[1]昆明医科大学第一附属医院神经内科,650032

出　　处：《中华神经科杂志》2021年第10期1064-1067,共4页Chinese Journal of Neurology

基　　金：云南省高层次卫生计生人才培养工程(L-2019018)。

摘　　要：抗接触蛋白相关蛋白2(CASPR2)抗体脑炎为罕见的自身免疫性脑炎,临床症状多变,影像学表现不典型,病情严重者预后不佳。可逆性后部白质脑病综合征在自身免疫性脑炎中鲜有报道,文中就1例合并可逆性后部脑病综合征的抗CASPR2抗体脑炎患者的临床资料及诊治过程进行回顾性分析,以提高临床医师对此罕见疾病合并不典型影像学表现的认识。Anti-contactin associated protein-like 2(CASPR2)antibody encephalitis is a rare autoimmune encephalitis with variable clinical symptoms and atypical imaging manifestations.The prognosis of the patients with severe disease is poor.Reversible posterior leukoencephalopathy syndrome is rarely reported in autoimmune encephalitis.The clinical data,diagnosis and treatment of a patient with anti-CASPR2 antibody encephalitis complicated with reversible posterior encephalopathy syndrome were reported,in order to improve the understanding of clinicians on the rare disease complicated with atypical imaging manifestations.

关 键 词：抗体 脑炎 接触蛋白相关蛋白2 后部白质脑病综合征 

分 类 号：R742[医药卫生—神经病学与精神病学]