ROS is essential for initiation of energy deprivation-induced autophagy  

作　　者：Choufei Wu Yixing Li Shu Zhong Yingcong Chen Yu Xie Yuyao Feng Weijing Yao Suping Fu Yanlan Zhu Liefeng Wang Yuting Chen Liqin Zhang Jingjing Tong Cong Yi 

机构地区：[1]Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province,School of Life Sciences,Huzhou University,Huzhou 313000,China [2]Department of Biochemistry,and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310058,China [3]School of Life Sciences,Central China Normal University,Wuhan 430079,China [4]College of Chemistry and Bio-Engineering,Yichun University,Yichun 336000,China [5]Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education,Gannan Medical University,Ganzhou 341000,China

出　　处：《Journal of Genetics and Genomics》2021年第6期512-515,共4页遗传学报（英文版）

基　　金：supported by the National Natural Science Foundation of China(32070739,31771528,and 91754107);Zhejiang Provincial Natural Science Foundation of China(LR21C070001);the National Basic Research Program of China(2017YFA0503402)to C.Yi;Natural Science Foundation for Young Scientists of China(81800085);Natural Science Foundation of Hubei Province,China(ZRMS2020002147)to J.Tong;Zhejiang Key R&D Program of China(2019C02030)to L.Zhang。

摘　　要：Autophagy is a highly conserved degradation process in which intracellular components are engulfed into a double membrane structure,known as the autophagosomes,and then delivered to lysosomes/vacuoles for degradation(Ohsumi,2014).Recently,autophagy has been found to be responsible for maintaining glucose homeostasis in adult animals(Karsli-Uzunbas et al.,2014).However,the molecular mechanism underlying energy deprivation-induced autophagy remains relatively unclear.

关 键 词：DEPRIVATION HOMEOSTASIS 

分 类 号：Q25[生物学—细胞生物学]