全人群肿瘤登记资料生存率分析方法的研究进展  

Progress on the Statistical Methods and Application of Survival Analysis for the Population-based Cancer Registration

作　　者：蒋宇飞 李卓颖 袁蕙芸[1,2] 项永兵[1,2,3] JIANG Yu-fei;LI Zhuo-ying;YUAN Hui-yun;XIANG Yong-bing(State Key Laboratory of Oncogenes and Related Genes,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200032,China;Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China;Shanghai Cancer Institute,Shanghai 200032,China)

机构地区：[1]上海交通大学医学院附属仁济医院癌基因及相关基因国家重点实验室,上海200032 [2]上海交通大学医学院附属仁济医院,t海200127 [3]上海市肿瘤研究所,上海200032

出　　处：《中国肿瘤》2021年第10期777-783,共7页China Cancer

基　　金：国家重点研发计划项目(2016YFC1302503)。

摘　　要：全人群肿瘤生存率是肿瘤登记资料分析最常用的统计指标。该指标对于评估一个国家或地区人群肿瘤防控策略有效性和公平性至关重要,也是分析当地人群肿瘤疾病负担的重要指标之一。全文系统回顾了全人群肿瘤登记资料统计分析研究中所涉及的生存率基本概念和方法,例如净生存率、观察生存率、期望生存率、相对生存率、标化相对生存率等;同时介绍了生存率分析时间窗选择或相对生存率统计模型等相关统计方法的进展,期望为肿瘤登记处开展生存资料分析提供一定的参考。The survival rate is the most commonly used statistic for the data analysis of population-based cancer registration.It is also one of the most important indices for evaluating the effectiveness and fairness of cancer prevention and control strategies for countries and regions,as well as one of statistics for measuring the cancer burden.This article systematically reviews the development of related basic concepts,such as net survival rate,observed survival rate,expected survival rate,relative survival rate and age-adjusted relative survival rate,etc.We also introduces the progresses on calculation methods involved in the survival analysis of cancer registration data,including the selection of time windows in survival analysis and statistical model for relative survival rate as well,expecting to provide guidance for the survival analysis in cancer registries.

关 键 词：肿瘤 肿瘤登记 生存率分析 净生存率 相对生存率 

分 类 号：R73-31[医药卫生—肿瘤]