超微超顺磁性氧化铁在头颈鳞癌淋巴转移MRI诊断中的研究进展  

Research progress of ultrafine superparamagnetic iron oxide in MRI diagnosis of lymphatic metastasis of head and neck squamous cell carcinoma

作　　者：楼锦涛 王志强[1] 卫来[1] LOU Jintao;WANG Zhiqiang;WEI Lai(Zhongshan Hospital Affiliated to Dalian University,Liaoning Dalian 116001,China)

机构地区：[1]大连大学附属中山医院,辽宁大连116001

出　　处：《现代肿瘤医学》2021年第22期4059-4062,共4页Journal of Modern Oncology

基　　金：国家自然科学基金项目(编号:81871413)。

摘　　要：超微超顺磁性氧化铁(USPIO)作为磁共振对比剂,可用来评价恶性肿瘤的淋巴结转移。与常规MRI对比,USPIO增强MRI能提高转移淋巴结检测的敏感性、特异性及准确性,并且能更好地鉴别转移及非转移淋巴结。本文就近年来USPIO增强MRI在头颈鳞癌(HNSCC)淋巴结转移中的相关研究及文献进行综述,评估USPIO增强MRI对检测HNSCC转移淋巴结的临床应用潜力及发展前景。Ultrafine superparamagnetic iron oxide(USPIO)is used as a magnetic resonance contrast agent to evaluate lymph node metastasis of malignant tumors.Compared with conventional MRI,USPIO enhanced MRI can improve the sensitivity,specificity and accuracy of metastatic lymph node detection,and can better distinguish metastatic and non-metastatic lymph nodes.This article reviews the research and literature on the lymph node metastasis of head and neck squamous cell carcinoma(HNSCC)with USPIO-enhanced MRI in recent years.To evaluate the clinical application potential and development prospects of USPIO-enhanced MRI for detecting HNSCC metastatic lymph nodes.

关 键 词：头颈部鳞状细胞癌 超微超顺磁性氧化铁 磁共振成像 淋巴转移 

分 类 号：R739.91[医药卫生—肿瘤]