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作 者:赵文华[1] ZHAO Wenhua(Department of Stomatology,Second Hospital of Traditional Chinese Medicine,Tai'an 271000,China)
机构地区:[1]山东省泰安市中医二院口腔科,山东泰安271000
出 处:《中国医药指南》2021年第29期25-27,共3页Guide of China Medicine
摘 要:目的探讨两种根管治疗方案对慢性牙髓炎患者口腔健康相关生活质量的影响。方法选取2019年12月至2020年12月期间参与的66例慢性牙髓炎患者,随机数字表法分成两组,每组33例,观察组患者采取的是一次法根管治疗,对照组采取的是多次法根管治疗。观察患者生活质量评分,用口腔健康影响程度量表(OHIP-14)评估患者生活质量,分值越低患者生活质量越高。治疗前、治疗后1周在患者空腹时抽取静脉血,用酶联免疫吸附法测定血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)水平。计算两组并发症发生率并行比较。结果OHIP-14评分比较,两组治疗前、治疗后1周差异均衡(P>0.05);治疗后6个月,观察组分值较高(P<0.05)。炎性因子水平比较,治疗前,两组数值均衡(P>0.05);治疗后1周,观察组IL-6、TNF-α、hs-CRP较低(P<0.05)。与对照组并发症比较,观察组发生率较低(P<0.05)。结论与多次法根管疗法比较,一次法根管疗法能够有效改善患者生活质量,改善患者的炎性因子水平。Objective To explore the effect of two root canal treatment options on oral health-related quality of life in patients with chronic pulpitis.Method A total of 66 patients with chronic pulpitis who participated in the period from December 2019 to December 2020 were selected and randomly divided into two groups with 33 cases in each group.Patients in the observation group were treated with one root canal treatment,while the patients in the control group were treated with multiple root canal treatments.Observe the patient's quality of life score and use the Oral Health Impact Scale(OHIP-14)to assess the patient's quality of life.The lower the score,the higher the quality of life of the patient.Before treatment and 1 week after treatment,draw venous blood from the patient on an empty stomach,and measure serum interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),and high-sensitivity C-reactive protein by enzyme-linked immunosorbent assay(hs-CRP)level.Calculate the complication rate of the two groups and compare them in parallel.Results Comparison of OHIP-14 scores showed that the difference between the two groups before treatment and 1 week after treatment was balanced(P>0.05);6 months after treatment,the observed component values were higher(P<0.05).Comparison of inflammatory factor levels,before treatment,the two groups were balanced(P>0.05);1 week after treatment,IL-6,TNF-αand hs-CRP were lower in the observation group(P<0.05).Compared with the control group,the incidence of complications in the observation group was lower(P<0.05).Conclusion Compared with multiple root canal therapy,single root canal therapy can effectively improve the quality of life of patients and improve the level of inflammatory factors in patients.
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