老年慢性创面动物模型的建立及研究进展  

Establishment and Research Progress of Animal Model of Chronic Wound in Elderly

作　　者：徐烽 樊炜静 张寅峰 严仕梦 柳国斌[2] XU Feng;FAN Weijing;ZHANG Yinfeng;YAN Shimeng;LIU Guobin(Shanghai University of traditional Chinese Medicine,Shanghai 20002,China;Shuguang Hospital Affiliated to Shanghai University of traditional Chinese Medicine,Shanghai 200023,China)

机构地区：[1]上海中医药大学,上海200023 [2]上海中医药大学附属曙光医院,上海200023

出　　处：《实验动物科学》2021年第4期73-77,共5页Laboratory Animal Science

基　　金：国家自然科学基金(No.81774310;No.81804095);上海市科学技术委员会科研计划项目(16401902200)。

摘　　要：在全球老龄化的大环境下,慢性创面在老年群体中的患病率不断升高,为了更好地探索常见老年慢性创面的发病机制及更有效地诊疗手段,需要建立适宜的动物模型。本文对压迫性溃疡创面、静脉性溃疡创面及糖尿病足创面三大占比较高的慢性创面疾病的动物模型建立方式、存在问题和未来发展进行概述。In the global environment of aging,the prevalence of chronic wounds in the elderly population is increasing.In order to better explore the pathogenesis of common chronic wounds in the elderly and more effective means of diagnosis and treatment,appropriate animals need to be established.This article summarizes the three animal disease models with high compressive ulcer wounds,venous ulcer wounds,and diabetic foot wounds,as well as their existing problems and future development.

关 键 词：慢性创面 动物模型 压迫性溃疡 静脉性溃疡 糖尿病足 

分 类 号：R-1[医药卫生]