金银花中绿原酸的积累和生物合成研究进展  

Research Progress on Accumulation and Biosynthesis of Chlorogenic Acid in Lonicerae japonicae

作　　者：徐萍 徐小博 郭晖[1] 许平辉 李凤梅 TATIANA Fotina XU Ping;XU Xiaobo;GUO Hui;XU Pinghui;LI Fengmei;TETIANA Fotina(College of Life Science and Basic medicine,Xinxiang University,Xinxiang 453003;Xinxiang Biocaro Biotech Co.,Ltd.,Xinxiang 453003;Faculty of Veterinary Medicine,Sumy National Agrarian University,Sumy 40021)

机构地区：[1]新乡学院生命科学与基础医学学院,新乡453003 [2]新乡博凯生物技术有限公司,新乡453300 [3]兽医学院苏梅国立农业大学,苏梅40021

出　　处：《食品工业》2021年第10期252-256,共5页The Food Industry

基　　金：新乡学院-新乡博凯生物横向合作项目(1344010022);河南省自然基金项目(212300410220);河南省高等学校重点科研项目(20A180025,21B180009)。

摘　　要：绿原酸是金银花的主要药用成分,随着生物技术的发展,揭示绿原酸的生物合成途径,将有助于通过基因工程方法来提高内源的绿原酸含量。近年来围绕如何提高金银花中绿原酸含量,尤其是在金银花中绿源酸的生物合成研究方面取得了很多进展。综述了金银花中绿原酸的影响因素、绿原酸生物合成途径及其调控方面的最新研究成果,以期为绿原酸的生物合成及调控研究提供参考。Chlorogenic acid is the main medicinal component of Lonicerae japonicae. With the development of biotechnology, the biosynthesis route of chlorogenic acid will be well revealed, which is help to improve the endogenous chlorogenic acid content through genetic engineering. In the past decade, many progresses have been obtained in how to improve the content of chlorogenic acid in Lonicerae japonicae, especially in the biosynthesis of chlorogenic acid. This paper summarizes the research results of factors affecting chlorogenic acid, chlorogenic acid biosynthesis route and its regulation in Lonicerae japonicae in the latest decade, hope for providing a theoretical reference for the biosynthesis and regulation of chlorogenic acid.

关 键 词：金银花 绿原酸 生物合成 

分 类 号：S567.79[农业科学—中草药栽培]