Solumbra技术在急性大动脉闭塞性脑梗死中的应用  

Application of Solumbra Technique in Acute Large Artery Occlusive Cerebral Infarction

作　　者：殷昊 赵勇 檀国祥 许啟伍 YIN Hao;ZHAO Yong;TAN Guo-xiang;XU Qi-wu(Department of Neurology,Tongling Municipal Hospital,Tongling 244000,China)

机构地区：[1]铜陵市立医院神经内科,安徽铜陵244000

出　　处：《南昌大学学报（医学版）》2021年第5期37-40,44,共5页Journal of Nanchang University：Medical Sciences

基　　金：铜陵市科技局项目(2017NS17)。

摘　　要：目的回顾性分析Solumbra技术在急性大动脉闭塞性脑梗死患者中的应用效果。方法选取2016年1月至2020年1月期间就诊的急性大动脉闭塞性脑梗死患者129例,按照取栓技术的不同分为2组:观察组(Solumbra技术)69例、对照组(常规支架取栓术)60例;比较2组取栓前及取栓后不同时间点(24 h、14 d和90 d)的美国国立卫生研究院卒中量表(NIHSS)评分;比较2组的血管再通率、改良Rankin评分、穿刺-再通时间(PRT)、发病-再通时间(ORT)、取栓次数及随访结局(栓子移位、颅内出血率、症状性颅内出血和死亡)。结果2组取栓前NIHSS评分无显著性差异(P>0.05);取栓后24 h、14 d和90 d,观察组NIHSS评分均低于对照组(均P<0.05)。对照组一次性取栓血管再通率(30.00%)、最终取栓血管再通率(71.67%)及Rankin预后良好率(43.33%)均分别低于观察组的49.27%、89.86%、69.57%(均P<0.05);对照组PRT、ORT、取栓次数均多于观察组(均P<0.05),栓子移位、颅内出血率亦均高于观察组(均P<0.05)。结论Solumbra技术用于对急性大动脉闭塞性脑梗死患者,其疗效较好,可提高血管再通率,改善神经功能,减少不良结局,有利于改善患者的预后。Objective To retrospectively analyze the application of Solumbra technique in patients with acute large artery occlusive cerebral infarction.Methods A total of 129 patients with acute large artery occlusive cerebral infarction who were admitted to Tongling Municipal Hospital from January 2016 to January 2020 were given conventional stent thrombectomy alone(control group,60 patients)or in combination with intravascular recanalization by using Solumbra technique(observation group,69 patients).The National Institutes of Health Stroke Scale(NIHSS)score was measured before and at 24 h,14 d and 90 d after thrombectomy.In addition,intravascular recanalization rate,modified Rankin Scale(MRS)score,puncture-to-reperfusion time(PRT),onset-to-reperfusion time(ORT),frequency of embolectomy and follow-up outcomes(thrombus displacement,intracranial hemorrhage,symptomatic intracranial hemorrhage and death)were compared between the two groups.Results There were no significant difference in NIHSS scores between the two groups before embolectomy(P>0.05).However,NIHSS scores in the observation group were lower than those in the control group at 24 h,14 d and 90 d after thrombectomy.Furthermore,the first-attempt recanalization rate,final recanalization rate and good Rankin prognosis rate in the control group(30.00%,71.67%and 43.33%,respectively)were lower than those in the observation group(49.27%,89.86%and 69.57%,respectively)(P<0.05).Moreover,PRT,ORT,frequency of embolectomy and incidence of thrombus displacement and intracranial hemorrhage in the control group were higher than those in the observation group(P<0.05).Conclusion Solumbra technique can effectively improve vascular recanalization rate,neurological function and prognosis and reduce adverse outcomes in patients with acute large artery occlusive cerebral infarction.

关 键 词：Solumbra技术 大动脉闭塞性脑梗死 急性 血管再通率 神经功能 

分 类 号：R743.33[医药卫生—神经病学与精神病学]