非酒精性脂肪性肝病与结直肠腺瘤性息肉相关性的研究进展  

Research advances in the association between nonalcoholic fatty liver disease and colorectal adenomatous polyps

作　　者：汤锦洪 王龙[1] TANG Jinhong;WANG Long(Department of Gastroenterology,The Sixth Affiliated Hospital of Shanghai Jiao Tong University,Shanghai 200233,China)

机构地区：[1]上海交通大学附属第六人民医院消化内科,上海200233

出　　处：《临床肝胆病杂志》2021年第11期2672-2675,共4页Journal of Clinical Hepatology

基　　金：上海交通大学附属第六人民医院院级科学研究基金(X-院内-2258)。

摘　　要：非酒精性脂肪性肝病(NAFLD)及结直肠腺瘤性息肉与代谢综合征(MS)的各个组分密切相关。归纳了近年来NAFLD与结直肠腺瘤性息肉相关性的研究,结果显示NAFLD与结肠直肠腺瘤性息肉风险增加有关。其中机制尚未完全明确,可能与胰岛素抵抗、慢性炎症反应、脂肪细胞因子、肠道菌群紊乱等因素有关。Nonalcoholic fatty liver disease(NAFLD)and colorectal adenomatous polyps are closely associated with the various components of metabolic syndrome.This article summarizes the recent studies on the association between NAFLD and colorectal adenomatous polyps,and the results show that NAFLD is associated with an increased risk of colorectal adenomatous polyps,while related mechanism remains unclear,which may be associated with insulin resistance,chronic inflammatory response,adipokines,and intestinal flora disturbance.

关 键 词：非酒精性脂肪性肝病 结肠腺瘤息肉病 结直肠肿瘤 

分 类 号：R575.5[医药卫生—消化系统]