酵母1号和2号染色体DNA的组成排列对比分析  

Comparative Analysis of the Composition and Arrangement of Yeast Chromosome 1 and 2 DNA

作　　者：刘建丽 周德良 靳文 LIU Jianli;ZHOU Deliang;JIN Wen(School of Water Resource and Environment Engineering,China University of Geosciences(Beijing),Beijing 100083,China;Beijing Zhongdianyida Technology Co.,Ltd.,Beijing 100190,China;Department of Clinical Medical Research Center,Inner Mongolia key laboratory of gene regulation of the metabolic disease,Inner Mongolia People’s Hospital,Hohhot 010010,China)

机构地区：[1]中国地质大学(北京)水资源与环境学院,北京100083 [2]北京中电易达科技有限公司,北京100190 [3]内蒙古自治区人民医院临床医学研究中心内蒙古自治区代谢紊乱疾病基因调控重点实验室,内蒙古呼和浩特010010

出　　处：《贵州大学学报（自然科学版）》2021年第6期44-49,共6页Journal of Guizhou University:Natural Sciences

基　　金：教育部全国教育科学规划资助项目(53200759777)。

摘　　要：酵母基因与高等真核生物基因具有较高的同源性。针对酵母1号和2号染色体DNA,通过脚本程序分别计算分析了:单核苷和双核苷组成百分比;3种类型双核苷的步距频次百分比。分析发现:单核苷和双核苷组成百分比在1号和2号染色体DNA上基本相同;无论哪一种双核苷,它们在1号和2号染色体DNA上交替出现的步距频次百分比几乎相同,它们在2条染色体上的排列存在一定的相似性。上述结果说明:酵母1号和2号染色体DNA没有明显的单核苷和双核苷组成偏好,它们的单核苷和双核苷组成具有较高程度的趋同性;酵母1号和2号染色体DNA可能具有较高相似度的双核苷排列分布。上述结果或许对酵母与高等真核生物的同源性研究分析具有一定的意义和价值。Yeast genes have high homology with higher eukaryotes genes.For yeast chromosome 1 and 2 DNA,we calculated and analyzed:the composition percentage of mononucleoside and dinucleoside;the spacing frequency percentage of three types of dinucleoside.The results show that:the composition percentages of mononucleoside and dinucleoside on chromosome 1 and 2 DNA were basically the same;no matter which dinucleoside,their spacing frequency percentage on chromosome 1 and 2 DNA were almost the same,and their arrangement on the two chromosomes were similar.These results indicate that:yeast chromosome 1 and 2 DNA have no obvious mononucleoside and dinucleoside composition preference,and their mononucleoside and dinucleoside composition have a high degree of convergence;yeast chromosome 1 and 2 DNA may have a high similarity of dinucleoside arrangement.These results may have some significance and value for the homology analysis between yeast and higher eukaryotes.

关 键 词：酵母 染色体DNA 组成百分比 步距频次百分比 核苷组成偏好 双核苷排列分布 

分 类 号：Q811.4[生物学—生物工程]