导管介入联合健胃清肠合剂对肠梗阻患者肠道屏障的影响  

Efficacy of catheter intervention and the Jianwei Qingchang mixture on intestinal barrier in patients with intestinal obstruction

作　　者：孙定平 孙尚龙 汪佳明[1] 杨维建[1] Sun Dingping

机构地区：[1]甘肃省中医院,甘肃兰州730050

出　　处：《中医临床研究》2021年第19期102-104,共3页Clinical Journal Of Chinese Medicine

基　　金：甘肃省中医药管理局项目(GZK-2018-26)。

摘　　要：目的:观察导管介入联合健胃清肠合剂对肠梗阻患者肠道屏障的影响。方法:本研究采取随机对照设计,依据纳入、排除标准选择肠梗阻患者60例,按住院号随机编号,然后从随机数字表产生的数字中,将奇数对应的患者编入观察组30例,偶数对应者编入对照组30例。观察组干预措施为基础治疗+导管介入+健胃清肠合剂。对照组为基础治疗+导管介入。治疗结束后对两组指标进行统计分析。结果:治疗后观察组血清白细胞介素-6、肿瘤坏死因子-α、二胺氧化酶、D-乳酸及内毒素水平显著低于对照组,而白细胞介素-22水平高于对照组,观察组和对照组上述指标比较,差异具有统计学意义(P<0.05)。结论:健胃清肠合剂可抑制或阻止肠道炎症,保护了肠屏障功能,值得推广。Objective:To observe efficacy of Catheter intervention and the Jianwei Qingchang mixture(健胃清肠合剂)on intestinal barrier in patients with intestinal obstruction.Methods:60 cases were divided into the observation group and the control group,30 cases in each.The observation group were given basic treatment+catheter intervention+the Jianwei Qingchang mixture.The control group was given basic treatment+catheter intervention.Results:IL-6,TNF-α,DAO,D-LAC and LPS levels in the observation group after treatment were significantly lower than the control group,while the IL-22 level was higher(P<0.05).Conclusion:The Jianwei Qingchang mixture can inhibit or prevent intestinal inflammation,protect the intestinal barrier function,and is worthy of promotion.

关 键 词：肠梗阻 健胃清肠合剂 肠道屏障 

分 类 号：R574.2[医药卫生—消化系统]