Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding:A case report  

作　　者：Long Cong Nguyen Khanh Truong Vu Trang Thi Thuy Vo Chau Ha Trinh Tan Dang Do Ngoc Thi Van Pham Tuyen Van Pham Thanh Tuan Nguyen Hiep Canh Nguyen Jeong-Sik Byeon 

机构地区：[1]Gastroenterology and Hepatology Center,Bach Mai Hospital,Hanoi 10000,Viet Nam [2]Department of Gastroenterology,School of Medicine and Pharmacy,Vietnam National University Hanoi,Hanoi 10000,Viet Nam [3]Radiology Center,Bach Mai Hospital,Hanoi 10000,Viet Nam [4]Pathology Center,Bach Mai Hospital,Hanoi 10000,Viet Nam [5]Department of Human Pathology,Kanazawa University Graduate School of Medicine,Kanazawa 920-8640,Japan [6]Department of Gastroenterology,Asan Medical Center,University of Ulsan College of Medicine,Seoul 05505,South Korea

出　　处：《World Journal of Clinical Cases》2021年第31期9670-9679,共10页世界临床病例杂志

基　　金：Supported by School of Medicine and Pharmacy,Vietnam National University Hanoi,Hanoi,Viet Nam,No.QGSP.2021.06.

摘　　要：BACKGROUND Brunner’s gland hyperplasia(BGH)is a rare benign lesion of the duodenum.Lipomatous pseudohypertrophy(LiPH)of the pancreas is an extremely rare disease.Because each condition is rare,the probability of purely coincidental coexistence of both conditions is extremely low.CASE SUMMARY We report a 26-year-old man presenting to our hospital with symptoms of recurrent upper gastrointestinal bleeding.Upper gastrointestinal endoscopy showed a huge pedunculated polypoid lesion in the duodenum with bleeding at the base of the lesion.Histopathological examination of the duodenal biopsy specimens showed BGH.Besides,abdominal computed tomography and magnetic resonance imaging revealed marked fat replacement over the entire pancreas,confirmed by histopathological evaluation on percutaneous pancreatic biopsies.Based on the radiological and histological findings,LiPH of the pancreas and BGH were diagnosed.The patient refused any surgical intervention.Therefore,he was managed with supportive treatment.The patient’s symptoms improved and there was no further bleeding.CONCLUSION This is the first well-documented case showing the coexistence of LiPH of the pancreas and BGH.

关 键 词：Lipomatous pseudohypertrophy PANCREAS Gastrointestinal bleeding Brunner’s gland Case report 

分 类 号：R576[医药卫生—消化系统]