Choriocarcinoma misdiagnosed as cerebral hemangioma:A case report  

作　　者：Hui-Qiong Huang Feng-Ming Gong Ru-Tie Yin Xiao-Juan Lin 

机构地区：[1]Gynecological Oncology of Biotherapy Laboratory,Department of Gynecology and Obstetrics,Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University),Ministry of Education,West China Second University Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China

出　　处：《World Journal of Clinical Cases》2021年第30期9174-9181,共8页世界临床病例杂志

摘　　要：BACKGROUND Choriocarcinoma is a subtype of gestational trophoblastic disease,gestational trophoblastic neoplasia.Patients with brain metastasis are rare and information on the optimal treatment and patient outcome is limited.In order to improve the prognosis of this disease,accurate and timely treatments are very important for the patient of brain metastasis by choriocarcinoma.CASE SUMMARY A 17-year-old unmarried girl was misdiagnosed with a cerebral hemangioma with intracranial hemorrhage in a local hospital after presentation with severe head pain.She underwent craniotomy three times for treatment.The pathological results of posterior intracranial hematoma showed choriocarcinoma,and the patient was diagnosed as choriocarcinoma(21 points in stage IV).After uterine artery embolization,etoposide,methotrexate,actinomycin D,cyclophosphamide,and vincristine chemotherapy for 7 cycles,and whole brain radiotherapy,the patient achieved remission.She has been followed for 2 years with no signs of tumor recurrence.CONCLUSION For female patients of childbearing age with an intracranial hematoma,the possibility of brain metastasis by choriocarcinoma should be considered.It is necessary to obtain a detailed history,including menstruation,beginning age of first sex,contraception,etc.The level ofβ-human chorionic gonadotropin should be tested at the beginning,and a stratified treatment should be administered according to the International Federation of Gynecology and Obstetrics staging and World Health Organization prognostic scoring systems.

关 键 词：Brain metastasis CHORIOCARCINOMA Uterine artery embolization CHEMOTHERAPY Whole brain radiotherapy CRANIOTOMY Case report 

分 类 号：R739.41[医药卫生—肿瘤]