糖尿病患者视网膜血管直径的变化与突发性耳聋的相关性  

Predictive Value of Changes in Retinal Vessel Diameter in Diabetic Patients for Sudden Deafness

作　　者：杨杭[1] 金芬芬 余陈翱 YANG Hang;JIN Fenfen;YU Chenhao(Jiangshan People’s Hospital,Jiangshan Zhejiang 324100,China)

机构地区：[1]浙江省江山市人民医院,浙江江山324100

出　　处：《中医药临床杂志》2021年第10期1951-1953,共3页Clinical Journal of Traditional Chinese Medicine

基　　金：2017年度江山市指导性科技计划项目(2017F50)。

摘　　要：目的:探讨2型糖尿病患者视网膜血管直径变化与突发性耳聋的相关性,探讨2型糖尿病合并突发性耳聋的危险因素。方法:选择2014—2019年在浙江省江山市人民医院住院的2型糖尿病患者60例,按有无突发性耳聋分组,观察组为2型糖尿病合并突发性耳聋患者,对照组为2型糖尿病患者。对所有患者计算视网膜中央动脉直径等效值(central retinal arteriolar equivalents,CRAE)、视网膜中央静脉直径等效值(central retinal venular equivalents,CRVE)和视网膜动静脉直径比值(arteriole-to-venule ratio,AVR),通过问卷调查和抽取静脉血获取其他突发性耳聋危险因素,研究2组患者CRAE和AVR的差异性。结果:2组患者CRAE、AVR、GLU比较差异有统计学意义。年龄、性别、糖尿病病程、高血压病史、吸烟史、TG、TC、BMI、SBP、DBP、HDL、LDL比较,差异无统计学意义。采用二元Logistic回归分析,AVR(OR=1.292,95%CI:1.081-1.545,P=0.005)对听力受损有影响。结论:糖尿病患者视网膜动静脉直径等效值和比值越小的患者,听力损失风险较大,故可以一定程度上预测糖尿病患者突发性耳聋发生风险,但需注意其他危险因素对于视网膜血管直径的影响。Objective:To investigate the relationship between the change of retinal blood vessel diameter and sudden deafness in patients with type 2 diabetes,and to explore the risk factors of type 2 diabetes with sudden deafness.Methods:A total of 60 patients with type 2 diabetes who were hospitalized in Jiangshan People’s Hospital in Zhejiang Province from 2014 to 2019 were selected and divided into groups according to the presence or absence of sudden deafness.The observation group was type 2 diabetes patients with sudden deafness,and the control group was type 2 Diabetics.Calculate central retinal arteriolar equivalents(CRAE),central retinal venular equivalents(CRVE),and arteriole-to-venule ratio(AVR)for all patients),through questionnaire survey and venous blood sampling to obtain other risk factors for sudden deafness,to study the difference of CRAE and AVR between the two groups of patients.Results:There were statistically significant differences in CRAE,AVR,and GLU between the two groups.There were no statistically significant differences in age,gender,course of diabetes,history of hypertension,history of smoking,TG,TC,BMI,SBP,DBP,HDL,and LDL.Using binary logistic regression analysis,AVR(OR=1.292,95%CI:1.081-1.545,P=0.005)has an impact on hearing loss.Conclusion:The smaller the equivalent value and ratio of the retina arteriovenous diameter in diabetic patients,the greater the risk of hearing loss,so the risk of sudden deafness in diabetic patients can be predicted to a certain extent.However,attention should be paid to the influence of other risk factors on the diameter of retinal blood vessels.

关 键 词：突发性耳聋 视网膜血管 糖尿病 

分 类 号：R774.1[医药卫生—眼科]