Preparation of selenofunctionalized heterocycles via iodosobenzene-mediated intramolecular selenocyclizations of olefins with diselenides  

作　　者：Peng-Fei Wang Wei Yi Yong Ling Liang Ming Gong-Qing Liu Yu Zhao 

机构地区：[1]School of Pharmacy,Nantong University,Nantong 226001,China

出　　处：《Chinese Chemical Letters》2021年第8期2587-2591,共5页中国化学快报（英文版）

基　　金：supported by the Natural Science Foundation of Jiangsu Province (No.BK20170439);Science and Technology Plan Projects of Nantong (Nos.JC2019102 and JC2020072)。

摘　　要：An intramolecular selenocyclizations of olefins mediated by a commercially available hypervalent iodine(Ⅲ) reagent,PhIO,was developed.This method provided access to a wide range of selenenylated heterocycles under ambient conditions.The striking advantages of this protocol over all previous methods include mild reaction conditions,easy operation,good yields,high levels of functional group compatibility,large-scale application and suitability for the late-stage functionalization of complex molecules of biological importance.

关 键 词：Selenocyclizations OLEFINS HETEROCYCLE Iodosobenzene DISELENIDES 

分 类 号：TQ266.1[化学工程—有机化工]