超高b值DWI-IVIM联合DCE-MRI对前列腺癌的诊断价值  

Study on the diagnostic value of ultra-high b-value DWI-IVIM combined with DCE-MRI in prostate cancer

作　　者：王松[1] 夏金翔[1] WANG Song;XIA Jinxiang(Medical Imaging Center,the Second People’s Hospital of Hefei,Anhui Province,Hefei,230011,China)

机构地区：[1]合肥市第二人民医院医学影像中心,安徽合肥230011

出　　处：《中国医药导报》2021年第28期156-159,共4页China Medical Herald

摘　　要：目的探讨超高弥散敏感系数(b值)弥散加权成像-体素内不相干运动(DWI-IVIM)联合动态对比增强磁共振成像(DCE-MRI)对前列腺癌的诊断价值。方法分析2017年2月至2020年7月合肥市第二人民医院收治的80例疑似前列腺癌患者的临床资料,所有受试者均行超高b值DWI-IVIM检查、DCE-MRI检查。超高b值DWI-IVIM诊断患者中央区、移行区和外周区的表观扩散系数(ADC)值及f值;比较前列腺癌灶区、增生区和正常区的容积转换常数(K_(trans))及速率常数(K_(ep))值;以病理检查结果为金标准,比较不同方法的诊断效能。结果前列腺癌患者中央区、移行区和外周区ADC值低于前列腺增生患者,f值高于前列腺增生患者,差异有统计学意义(P<0.05)。前列腺癌灶区、增生区和正常区K_(trans)、K_(ep)值比较,差异有统计学意义(P<0.05)。超高b值DWI-IVIM检测的灵敏度为91.84%,特异性为77.42%;DCE-MRI检测的灵敏度为91.84%,特异性为74.19%;联合检测的灵敏度为95.92%,特异性为90.32%。结论相较于超高b值DWI-IVIM或DCE-MRI单一检测,联合检测的灵敏度和特异性均增高,对于前列腺癌具有更高的诊断效能。Objective To investigate the diagnostic value of ultra-high multiple diffusion sensitivity coefficients(b-value)diffusion weighted imaging-intravoxel incoherent motion(DWI-IVIM)combined with dynamic contrast-enhancement magnetic resonance imaging(DCE-MRI)in prostate cancer.Methods The clinical data of 80 patients with suspected prostate cancer admitted to the Second People’s Hospital of Hefei from February 2017 to July 2020 were analyzed.The apparent diffusion coefficient(ADC)and f values of the central region,transitional region,and peripheral region of patients diagnosed by ultra-high b-value DWI-IVIM;volume conversion constant(K_(trans))and rate constant(K_(ep))values of prostate cancer focal area,hyperplastic area,and normal area were compared;pathological examination results were taken as the gold standard to compare the diagnostic efficacy of different methods.Results ADC values of central region,transitional region,and peripheral region of prostate cancer patients were lower than those of prostate hyperplasia patients,and f values were higher than those of prostate hyperplasia patients,and the differences were statistically significant(P<0.05).There were significant differences in K_(trans) and K_(ep) values between prostate cancer focal area,hyperplasia area,and normal area(P<0.05).The sensitivity and specificity of ultra-high b-value DWI-IVIM were 91.84%and 77.42%respectively;the sensitivity and specificity of DCE-MRI were 91.84%and 74.19%respectively;the sensitivity and specificity of the combined detection were 95.92%and 90.32%respectively.Conclusion Comparing with ultrahigh b-value DWI-IVIM or DCE-MRI single detection,the sensitivity and specificity of combined detection are significantly increased,and has higher diagnostic efficacy for prostate cancer.

关 键 词：前列腺癌 多弥散敏感系数 弥散加权成像 体素内不相干运动 动态对比增强磁共振成像 

分 类 号：R737.25[医药卫生—肿瘤]