炎症标志物对鼻咽癌患者预后的预测价值  

The prognostic role of inflammatory markers in patiens with nasopharyngeal carcinoma

作　　者：李倩[1] 胡钦勇[1] LI Qian;HU Qinyong(Cancer Center,Renmin Hospital of Wuhan University,Hubei Province,Wuhan430060,China)

机构地区：[1]武汉大学人民医院肿瘤中心,湖北武汉430060

出　　处：《中国医药导报》2021年第29期41-44,55,共5页China Medical Herald

基　　金：国家自然科学基金资助项目(81670144)。

摘　　要：炎症在许多恶性肿瘤的发生、发展中发挥着十分重要的作用。炎症标志物因为其检测费用廉价,结果稳定、方便的特点,目前已广泛应用于肺癌、胃癌、结直肠癌、肝癌、胰腺癌等恶性肿瘤以预测患者的预后,成为近年来肿瘤研究的热点。然而,炎症标志物在鼻咽癌中的研究相对较少且结论不一。因此,本文就目前研究较多的炎症标志物,如中性粒细胞淋巴细胞比、血小板淋巴细胞比和淋巴细胞单核细胞比,及近年来新兴的炎症标志物如全身免疫炎症指数、全身炎症反应指数、预后营养指数、格拉斯哥预后评分及C反应蛋白白蛋白比等在鼻咽癌中的研究进展进行概述,以期对鼻咽癌传统的预后相关因素做一补充,有助于为患者提供更好的个性化治疗方案。Inflammation plays an important role in the occurrence and development of various cancers.Inflammatory markers have the characteristics of low cost,stable results and convenience,which have been widely used in lung cancer,gastric cancer,colorectal cancer,liver cancer,pancreatic cancer and other malignant tumors to predict the prognosis of patients.Inflammation markers have been a hot spot in cancer research in recent years.However,there are relatively few studies on inflammatory markers in nasopharyngeal carcinoma and the conclusions are different.Therefore,this article reviews the widely studied inflammatory markers,such as neutrophil-lymphocyte ratio,platelet-lymphocyte ratio,and lymphocyte-to-monocyte ratio,as well as the recent development of emerging inflammatory markers such as systemic immune inflammation index,systemic inflammation response index,prognostic nutritional index,Glasgow prognostic score and C-reactive protein/albumin ratio in nasopharyngeal carcinoma.It aims to supplement the traditional prognostic factors of nasopharyngeal carcinoma and help to provide better personalized treatment plans for cancer patients.

关 键 词：炎症标志物 鼻咽癌 预后 预测价值 

分 类 号：R739.63[医药卫生—肿瘤]