正性暗示联合渐进式康复对老年帕金森病患者认知功能、自我效能及血清神经递质水平的影响  

Effect of positive suggestion combined with progressive rehabilitation on cognitive function,self-efficacy and serum neurotransmitter levels in elderly patients with Parkinson's disease

作　　者：申敏[1] 李任增[1] 贾爱兰[2] 樊润润[1] 徐艳丽[1] SHEN Min;LI Renzeng;JIAAilan(Anyang Third People's Hospital,Anyang 455000,China)

机构地区：[1]安阳市第三人民医院,安阳455000 [2]新乡医学院第一附属医院神经内科

出　　处：《国际精神病学杂志》2021年第5期919-922,共4页Journal Of International Psychiatry

基　　金：河南省医学科技攻关计划项目(编号:2018010050)。

摘　　要：目的探讨采用正性暗示联合渐进式康复训练对老年帕金森(PD)患者的认知功能、自我效能以及血清神经递质水平的影响。方法纳入2018年3月~2020年9月期间在我院接受治疗的123例老年帕金森患者作为观察对象,掷币法将其分成2组,两组患者均进行常规药物治疗,对照组61例接受正性暗示联合常规护理方案,观察组62例患者在对照组护理基础上加以渐进式康复护理,比较两组患者认知功能、自我效能以及血清神经递质水平变化。结果干预后,两组患者UPDRS评分明显降低,且观察组较对照组更低(P<0.05);两组患者MoCA评分及GSES评分明显升高,且观察组较对照组更高(P<0.05);两组患者BDNF及5-HT水平明显升高,且观察组较对照组更高(P<0.05)。结论正性暗示联合渐进式康复干预能有效提高PD患者自我效能感,显著增加神经递质水平,改善患者认知功能。Objective To explore the effect of positive suggestion combined with progressive rehabilitation training on cognitive function,self-efficacy and serum neurotransmitter levels in elderly Parkinson's patients.Methods A total of 123 elderly Parkinson's patients who were treated in our hospital from March 2018 to September 2020 were included as observation objects.They were divided into two groups by coin tossing.Both groups were treated with conventional drugs,61 cases in the control group accepted positive suggestion combined with conventional nursing program,62 patients in the observation group received gradual rehabilitation care based on the nursing of the control group,and the changes in cognitive function,self-efficacy and serum neurotransmitter levels of the two groups were compared.Results After the intervention,the UPDRS scores of the two groups of patients were significantly reduced,and the observation group was lower than the control group,and the difference between the groups was significant(P<0.05).The MoCA score and GSES score of the two groups were significantly increased,and the observation group was higher than those in control group(P<0.05).The levels of BDNF and 5-HT in the two groups are significantly higher,and the observation group is higher than those in control group,the difference between the groups is significant(P<0.05).Conclusion Positive suggestion combined with progressive rehabilitation intervention can effectively improve the selfefficacy of PD patients,significantly increase the level of neurotransmitters,and improve the cognitive function of patients.

关 键 词：正性暗示 渐进式康复 帕金森病 认知功能 神经递质 

分 类 号：R749.1[医药卫生—神经病学与精神病学]