对比PET/MRI与PET/CT检出肝转移癌效能  

Comparison on efficacy of PET/MRI and PET/CT for detecting liver metastases

作　　者：于军 任东栋 任春玲 李洋 蔡君 张莺[2] YU Jun;REN Dongdong;REN Chunling;LI Yang;CAI Jun;ZHANG Ying(Department of Nuclear Medicine,Ningbo Mingzhou Hospital,Ningbo 315100,China;Department of Nuclear Medicine,the Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China)

机构地区：[1]宁波明州医院核医学科,浙江宁波315100 [2]浙江大学医学院附属第二医院核医学科,浙江杭州310009

出　　处：《中国医学影像技术》2021年第11期1609-1613,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的对比观察PET/MRI与PET/CT检出肝转移癌的效能。方法纳入78例共409个肝转移癌病灶,比较PET/CT及PET/MRI检出肝转移癌的阳性率。对A组50例283个病灶先行PET/CT后行PET/MR检查,B组28例126个病灶先行PET/MR后行PET/CT。采用Spearman秩相关分析和Wilcoxon秩和检验评价组内不同检查方法所获病灶最大标准摄取值(SUV max)的相关性及其差异。结果PET/MRI对肝转移癌的检出率(381/409,93.15%)明显高于PET/CT(285/409,69.68%,P<0.05)。A组PET/MRI的阳性率(266/283,93.99%)明显高于PET/CT(197/283,69.61%,P<0.05);PET/MRI与PET/CT的SUV max高度相关(r=0.84,P<0.05),而PET/MRI的SUV max显著高于PET/CT的SUV max(P<0.05)。B组PET/MRI阳性率(115/126,91.27%)明显高于PET/CT(88/126,69.84%,P<0.05);PET/MRI与PET/CT的SUV max中度相关(r=0.74,P<0.05),且差异无统计学意义(P>0.05)。结论PET/MRI检出肝转移癌效果优于PET/CT;二者所获SUV max相关性较好。Objective To observe the efficacy of PET/MRI and PET/CT for detecting liver metastases.Methods A total of 409 liver metastases were observed in 78 patients,the positive rates of PET/CT and PET/MRI for detecting liver metastases were compared.Fifty patients(283 lesions)in group A underwent first PET/CT and then PET/MR,while 28 patients(126 lesions)in group B underwent first PET/MR and then PET/CT.Spearman rank correlation analysis and Wilcoxon signed rank test were performed to compare the correlations and differences of the maximum standard uptake value(SUV_(max))of liver metastases obtained with two methods in each group.Results The positive rate of PET/MRI for detecting liver metastases(381/409,93.15%)was significantly higher than that of PET/CT(285/409,69.68%,P<0.05).In group A,the positive rate of PET/MRI(266/283,93.99%)for detecting liver metastases was significantly higher than that of PET/CT(197/283,69.61%,P<0.05),and SUV_(max) obtained with PET/MRI was highly correlated with that obtained with PET/CT(r=0.84,P<0.05),while SUV_(max) obtained with PET/MRI was significantly higher than that obtained with PET/CT(P<0.05).In group B,the positive rate of PET/MRI(115/126,91.27%)was significantly higher than that of PET/CT(88/126,69.84%,P<0.05),and SUV_(max) obtained with PET/MRI was moderately correlated with that obtained with PET/CT(r=0.74,P<0.05),but no significant difference of SUV_(max) was found between PET/CT and PET/MRI(P>0.05).Conclusion PET/MRI was better than PET/CT for detecting liver metastases,and good correlation existed between SUV_(max) obtained with PET/MRI and PET/CT.

关 键 词：肿瘤转移 正电子发射断层显像 体层摄影术 X线计算机 磁共振成像 

分 类 号：R735.7[医药卫生—肿瘤] R817.4[医药卫生—临床医学]