ICU重症急性胰腺炎治疗中肠内营养治疗的应用及有效性研究  

Study on the Application and Effectiveness of Enteral Nutrition Therapy in the Treatment of Severe Acute Pancreatitis in ICU

作　　者：苏琴 白燕 SU Qin;BAI Yan(Department of Critical Care Medicine,Second People's Hospital of Qujing City,Qujing,Yunnan Province,655000 China;Department of Nephrology,The Second People's Hospital of Qujing City,Qujing,Yunnan Province,655000 China)

机构地区：[1]曲靖市第二人民医院重症医学科,云南曲靖655000 [2]曲靖市第二人民医院肾病学科,云南曲靖655000

出　　处：《中外医疗》2021年第25期28-31,共4页China & Foreign Medical Treatment

摘　　要：目的分析ICU重症急性胰腺炎治疗中肠内营养治疗的应用及有效性。方法便利选择该院2018年3月—2020年3月ICU重症急性胰腺炎患者共63例,按照随机数字表法分为两组,对照组(n=32)给予早期肠外营养支持,观察组(n=31)早期肠内营养支持。比较两组治疗效果。结果观察组住院时间(8.14±1.24)d,短于对照组的(10.21±2.24)d,差异有统计学意义(t=4.517,P<0.05);1周后患者机体营养状况水平血清白蛋白、血红蛋白、血清总蛋白、肿瘤坏死因子-α和超敏C反应蛋白优于对照组,差异有统计学意义(t=2.449、2.387、2.628、14.077、6.302,P<0.05);观察组总有效率100.00%高于对照组75.00%,差异有统计学意义(χ^(2)=6.765,P<0.009);观察组并发症6.45%少于对照组31.25%,差异有统计学意义(χ^(2)=6.280,P<0.012)。结论早期肠内营养支持对ICU重症急性胰腺炎患者效果确切,可更好改善患者的营养状况,对机体炎症状况进行有效控制,减少并发症的发生,缩短住院的时间,值得推广和应用。Objective To analyze the application and effectiveness of midgut nutrition in ICU treatment of severe acute pancreatitis.Methods A total of 63 patients with severe acute pancreatitis in ICU in the hospital from March 2018 to March 2020 were conveniently selected and divided into two groups by random number table method.The control group(n=32)received early parenteral nutrition support,and the observation group(n=31)received early enteral nutrition support.The therapeutic effects of the two groups were compared.Results The length of hospitalization in the observation group was(8.14±1.24)d,shorter than that in the control group(10.21±2.24)d,and the difference was statistically significant(t=4.517,P<0.05).After 1 week,the nutritional status of patients with serum albumin,hemoglobin,total serum protein,tumor necrosis factor-αand hypersensitive C-reactive protein were better than those of control group,the difference was statistically significant(t=2.449,2.387,2.628,14.077,6.302,P<0.05).The total effective rate of observation group was 100.00%higher than that of control group 75.00%,and the difference was statistically significant(χ^(2)=6.765,P<0.009).The complication rate in the observation group 6.45%were less than those in the control group 31.25%,and the difference was statistically significant(χ^(2)=6.280,P<0.012).Conclusion Early enteral nutrition support has a definite effect on ICU patients with severe acute pancreatitis,can better improve the nutritional status of patients,effectively control the body inflammation,reduce the occurrence of complications,shorten the length of hospital stay,and is worthy of promotion and application.

关 键 词：ICU重症急性胰腺炎 肠内营养治疗 营养状况 炎症指标 

分 类 号：R576[医药卫生—消化系统]