早期液体复苏联合肠内营养对中重症胰腺炎治疗疗效分析  

Analysis of the Curative Effect of Early Fluid Resuscitation Combined with Enteral Nutrition in the Treatment of Moderate and Severe Pancreatitis

作　　者：杨珺[1] YANG Jun(Department of Gastroenterology,Liyang People's Hospital,Liyang,Jiangsu Province,213300 China)

机构地区：[1]溧阳市人民医院消化内科,江苏溧阳213300

出　　处：《世界复合医学》2021年第9期166-169,共4页World Journal of Complex Medicine

摘　　要：目的分析中重症胰腺炎患者行早期液体复苏、肠内营养联合治疗的临床效果与应用价值。方法选择2018年7月—2020年3月该院收治中重症胰腺炎患者73例进行观察分析,随机分作两组,对照组(36例)患者采取常规综合治疗,观察组(37例)患者在其基础上采用早期液体复苏、肠内营养支持联合治疗,对比两组治疗效果,观察对比两组患者治疗后各项症状表现改善时间、体质量变化及住院总时间,观察患者治疗后出现不良反应类型,计算总发生概率。结果观察组临床治疗总有效率97.30%明显高于对照组,差异有统计学意义(χ^(2)=4.753,P<0.05)。观察组患者通过治疗后腹胀改善时间(30.39±12.14)min、恶心呕吐改善时间(33.77±15.19)min、发热改善时间(92.93±21.25)min、住院总时间(13.79±1.44)d均明显短于对照组,体质量减少(2.33±1.01)kg相比对照组较低,差异有统计学意义(t=7.237、5.398、5.480、20.871、15.362,P<0.05)。另外两组患者出现不良反应的概率差异无统计学意义(χ^(2)=0.001,P>0.05)。结论中重度胰腺炎患者行早期液体复苏配合肠内营养干预治疗效果确切,能够改善患者免疫功能,安全性佳,值得推广应用。Objective To analyze the clinical effect and application value of early fluid resuscitation and enteral nutrition combined therapy in patients with severe pancreatitis.Methods From July 2018 to March 2020,73 patients with moderate to severe pancreatitis admitted to the hospital were selected for observation and analysis,and they were randomly divided into two groups,patients in the control group(36 cases)were treated with conventional comprehensive treatment,and patients in the observation group(37 cases)were treated with a combination of early fluid resuscitation and enteral nutrition support,compare the treatment effects of the two groups,observe and compare the improvement time,weight change and total length of hospitalization of the two groups of patients after treatment,observe the types of adverse reactions after treatment,and calculate the total probability of occurrence.Results The total effective rate of clinical treatment in the observation group was 97.30%significantly higher than that in the control group,the difference was statistically significant(χ^(2)=4.753,P<0.05).In the observation group,the time to improve abdominal distension(30.39±12.14)min,nausea and vomiting(33.77±15.19)min,fever improvement time(92.93±21.25)min,and total hospital stay(13.79±1.44)d after treatment were significantly shorter than the control group,the weight loss(2.33±1.01)kg was lower than that of the control group,the difference was not statistically significant(t=7.237,5.398,5.480,20.871,15.362,P<0.05).There was no significant difference in the probability of adverse reactions between the other two groups of patients,the difference was statistically significant(χ^(2)=0.001,P>0.05).Conclusion Early fluid resuscitation combined with enteral nutrition intervention treatment for patients with moderate to severe pancreatitis has a definite effect,which can improve the immune function of patients and is of good safety.Therefore,it is worthy of popularization and application.

关 键 词：早期液体复苏 肠内营养 重症胰腺炎 疗效 

分 类 号：R576[医药卫生—消化系统]