药师参与肿瘤疼痛评估指南的实践与需求  

Pharmacists’Involvement in and Demands of Cancer Pain Assessment Guidelines

作　　者：张露[1,2] 黄行行 黄娅敏 杨永榆 王晨[4] 李国辉[5] 肖坚[1,2] Zhang Lu;Huang Hangxing;Huang Yamin;Yang Yongyu;Wang Chen;Li Guohui;Xiao Jian(Department of Pharmacy,Xiangya Hospital,Central South University,Changsha 410008,Hunan,China;Laboratory for Rational and Safe Use of Elderly,National Medical Research Center for Geriatric Disorders(Xiangya Hospital),Central South University,Changsha 410008,Hunan,China;Department of Pharmacy,the Second People’s Hospital of Beihai,Beihai 536000,Guangxi,China;Department of Pharmacy,Tianjin Medical University Cancer Institute&Hospital,Tianjin 300060,China;Department of Pharmacy,Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)

机构地区：[1]中南大学湘雅医院药学部,长沙410008 [2]国家老年疾病临床医学研究中心-老年合理用药与安全用药研究室,长沙410008 [3]北海市第二人民医院药学部,广西北海536000 [4]天津医科大学肿瘤医院药剂科,天津300060 [5]中国医学科学院北京协和医学院肿瘤医院药剂科,北京100021

出　　处：《肿瘤预防与治疗》2021年第10期937-941,共5页Journal of Cancer Control And Treatment

基　　金：湖南省自然科学基金(编号:2021JJ31043);长沙市自然科学基金(编号:kq 2007039);国家老年疾病临床医学研究中心适宜技术推广项目(编号:XYYYJSTG-15);并行与分布处理国防科技重点实验室稳定支持项目(编号:WDZC20205500121);中南大学研究生自主探索创新项目(编号:2021zz ts1040)。

摘　　要：目的:对药师在疼痛管理中的作用及国内外肿瘤疼痛评估指南的实践做简要介绍,提出应制定由药师参与或主导的肿瘤疼痛药学评估指南,确保疼痛评估准确、疼痛管理有效。方法:以"疼痛""癌痛""疼痛评估"关键词在中国知网、万方、维普、SinoM ed数据库检索;以"pain""cancer pain""pain assessment"为关键词在PubM ed、EMBASE、Web of Science、Cochrane Library数据库检索,同时检索国内外主要临床实践指南网站如美国国家综合癌症网络(National Comprehensive Cancer Network,NCCN)、国际指南协作网(Guidelines International Network,GIN)、美国国立临床指南数据库(National Guidelines Database,NGC)、英国国家卫生与临床优化研究所(National Institute for Health and Care Excellence,NICE)、国家卫生计生委员会及其下属机构、国内权威医学协会和机构及其他较为权威的专家小组或专业委员会等出版的癌痛临床实践指南,并辅以手动文献检索,提取数据并整理分析。结果:目前国内外制定了许多肿瘤疼痛评估指南,虽然在一定程度上促进了疼痛评估的规范,但仍存在疼痛评估流程不详细等问题,加上大多数都并未由药师主导或参与,一定程度上限制了药物治疗评价的深度和广度。结论:我国应尽快制定详尽、全面的肿瘤疼痛药学评估指南,以药师专业知识为依托,确保疼痛评估全面、准确,有效改善患者的临床结局。Objective:To briefly introduce the roles of pharmacists in pain management and their involvement in cancer pain assessment guidelines at home and abroad,and suggest that pharmacists should participate in or lead the development of cancer pain assessment guidelines to ensure accurate pain assessment and effective pain management.Methods:We searched the keywords of‘pain’,‘cancer pain’and‘pain assessment’in databases of CNKI,Wanfang,VIP,SinoMed,PubMed,EMBASE,Web of Science and Cochrane Library,and in cancer pain assessment guidelines published by websites of National Comprehensive Cancer Network(NCCN,US),Guidelines International Network(GIN),National Clinical Guidelines Database(NGC,US)National Institute for Health and Care Excellence(NICE,UK),as well as National Health and Family Planning Commission and its subsidiaries,domestic authoritative medical associations and institutions,and other authoritative panels or professional committees.The data extracted were then analyzed.Results:At present,many cancer pain assessment guidelines have been formulated at home and abroad,which promotes the norms of pain assessment to a certain extent,though,there are still problems such as undetailed pain assessment process.Most of them,however,were absent from guidance or participation by pharmacists,limiting the depth and breadth of drug use evaluation to some extent.Conclusion:Relying on professional knowledge of pharmacists,detailed and comprehensive cancer pain assessment guidelines should be formulated as soon as possible,aiming to ensure a comprehensive and accurate pain assessment and an effective improvement in clinical outcome of patients.

关 键 词：肿瘤疼痛 疼痛评估 药学 指南 疼痛管理 

分 类 号：R730.53[医药卫生—肿瘤] R730.6[医药卫生—临床医学]