食管胃底静脉曲张内镜下治疗后并发OPSI的诊治体会  

The experience in diagnosis and therapy of OPSI after endoscopic treatment of esophagogastric varices

作　　者：邓彩虹 李坪[1] 梁秀霞[1] 周玉玲[1] 林毅军[1] DENG Caihong;LI Ping;LIANG Xiuxia;ZHOU Yuling;LIN Yijun(Department of Gastroenterology,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China)

机构地区：[1]首都医科大学附属北京地坛医院消化内科,北京100015

出　　处：《胃肠病学和肝病学杂志》2021年第11期1313-1317,共5页Chinese Journal of Gastroenterology and Hepatology

摘　　要：脾切除后凶险性感染(overwhelming post-splenectomy infection,OPSI)是一种脾切除术后出现的致命性脓毒症,病死率高达50%。作为治疗食管胃底静脉曲张的有效手段,脾切除术已广泛应用于临床,故当临床医师治疗食管胃底静脉曲张伴有脾切除术的患者时,需高度警惕OPSI。关于食管胃底静脉曲张内镜下治疗并发OPSI的研究,目前国际及国内未见类似文献报道。故本研究总结了我院治疗的5例食管胃底静脉曲张内镜下治疗并发OPSI患者的疾病特征、诊治经过及预后,旨在探讨内镜下治疗后并发OPSI的发病特点及治疗方案,并为后续临床研究奠定基础;同时提升临床医师对该病的认识,提升诊疗水平。Overwhelming post-splenectomy infection(OPSI)is a fatal infection after splenectomy,the fatality rate of OPSI is 50%.As an important treatment of portal hypertension complicated with esophagogastric varices,splenectomy has been widely used.Therefore,when doctors treat patients with esophagogastric varices and splenectomy,they should be highly vigilant against OPSI.At present,there are no similar studies on endoscopic cyanoacrylate injection of esophagogastric varices complicated with OPSI at home and abroad.This study is about the diagnosis,treatment and prognosis of OPSI after endoscopic cyanoacrylate injection of esophagogastric varices in 5 patients who had underwent splenectomy for esophagogastric in our hospital.The purpose of this study is to explore the characteristics and treatment of OPSI after endoscopic treatment,lay a foundation for follow-up research,then enhance doctors'understanding of the disease and improve the level of diagnosis and treatment.

关 键 词：脾切除后凶险性感染 食管胃底静脉曲张 内镜下组织胶治疗 

分 类 号：R571[医药卫生—消化系统]