探讨内镜下经鼻蝶入路手术治疗垂体腺瘤卒中的临床价值  

Clinical value of endoscopic transsphenoidal approach in the treatment of pituitary adenoma apoplexy

作　　者：魏庆生 WEI Qing-sheng(Liaoyang Second People’s Hospital,Liaoyang 111000,China)

机构地区：[1]辽阳市第二人民医院,111000

出　　处：《中国现代药物应用》2021年第21期5-7,共3页Chinese Journal of Modern Drug Application

摘　　要：目的分析内镜下经鼻蝶入路手术治疗垂体腺瘤卒中的临床效果。方法60例垂体腺瘤卒中患者,随机分为对照组和观察组,每组30例。观察组采用鼻内镜下经鼻蝶入路手术,对照组采用显微镜经鼻蝶入路手术。比较两组肿瘤切除情况、视野指标、临床指标、并发症发生情况。结果观察组肿瘤完全切除率高于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组视野平均缺损(MD)(6.25±3.39)dB低于对照组的(9.87±3.21)dB,加权视野指数(VFI)(89.63±12.37)%高于对照组的(77.61±14.12)%,差异具有统计学意义(P<0.05)。观察组术中出血量(45.28±7.51)ml少于对照组的(80.36±8.26)ml,手术时间(93.32±8.64)min和术后住院时间(4.01±1.25)d短于对照组的(166.48±17.21)min、(6.92±1.53)d,差异均具有统计学意义(P<0.05)。观察组并发症发生率6.67%低于对照组的30.00%,差异具有统计学意义(χ^(2)=5.455,P=0.020<0.05)。结论内镜下经鼻蝶入路手术在垂体腺瘤卒中治疗中临床效果明显,除改善视野外,有助于肿瘤切除率提高,且具有较高的安全性。Objective To analyze the clinical effect of endoscopic transsphenoidal approach in the treatment of pituitary adenoma apoplexy.Methods A total of 60 patients with pituitary adenoma apoplexy were randomly divided into the control group and the observation group,with 30 cases in each group.The observation group underwent transsphenoidal surgery by nasal endoscopy,and the control group underwent transsphenoidal surgery by microscope.The tumor resection,visual field indicators,clinical indicators,and complications were compared between the two groups.Results The complete tumor resection rate in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the mean deviation(MD)(6.25±3.39)dB of the observation group was lower than(9.87±3.21)dB of the control group,and the visual field index(VFI)(89.63±12.37)%was higher than(77.61±14.12)%of the control group.All the differences were statistically significant(P<0.05).The intraoperative blood loss(45.28±7.51)ml of the observation group was less than(80.36±8.26)ml of the control group,and the operation time(93.32±8.64)min,and postoperative hospitalization time(4.01±1.25)d were shorter than(166.48±17.21)min and(6.92±1.53)d of the control group.All the differences were statistically significant(P<0.05).The complication rate 6.67%of the observation group was lower than 30.00%of the control group,and the difference was statistically significant(χ^(2)=5.455;P=0.020<0.05).Conclusion Endoscopic transsphenoidal approach has obvious clinical effect in the treatment of pituitary adenoma apoplexy.In addition to improving visual field,it is helpful to increase tumor resection rate and has high safety.

关 键 词：内镜 经鼻蝶入路手术 垂体腺瘤卒中 

分 类 号：R736.4[医药卫生—肿瘤]