阿司匹林急诊治疗血栓性脑梗死的效果及安全性研究  

Study on the Efficacy and Safety of Aspirin in Emergency Treatment of Thrombotic Cerebral Infarction

作　　者：潘定斌 陈志煌 陈晓 PAN Dingbin;CHEN Zhihuang;CHEN Xiao(Fuzhou Second Hospital,Fuzhou 350007,China;不详)

机构地区：[1]福州市第二医院,福建福州350007

出　　处：《中外医学研究》2021年第29期126-128,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究对血栓性脑梗死患者使用阿司匹林急诊治疗的效果及安全性。方法:研究开展时间是2018年6月-2020年12月,将此阶段在本医院接受急诊治疗的血栓性脑梗死患者纳入研究中,共计122例,结合随机数字表法将所有患者均分成样本量一致的两组,即试验组(n=61)和对照组(n=61),均接受常规治疗,前者增加阿司匹林治疗。比照两组患者治疗前后的神经功能、炎症因子水平、治疗效果及不良反应。结果:相比治疗前,治疗后两组患者的神经功能评分与各项炎症因子水平均降低,且两组患者的降低幅度进行比照,试验组患者的降低幅度均更大;两组患者的治疗总有效率进行对比,试验组患者更高;两组患者的不良反应总发生率进行对比,试验组患者更低,差异均有统计学意义(P<0.05)。结论:对血栓性脑梗死患者使用阿司匹林急诊治疗具有积极作用,能够有效缓解患者的临床症状,使其神经功能改善,能够减轻患者的炎症反应,且用药安全性高,患者出现的不良反应少,值得在临床广泛应用。Objective:To study the efficacy and safety of Aspirin emergency treatment for patients with thrombotic cerebral infarction.Method:The study was carried out from June 2018 to December 2020.Patients with thrombotic cerebral infarction who received emergency treatment in this hospital at this stage were included in the study,a total of 122 cases,combined with random number table method,all patients were divided into same sample size,namely the experimental group(n=61)and the control group(n=61),received conventional treatment,the former increased Aspirin treatment.The neurological function,inflammatory factor levels,treatment effect and adverse reactions of the two groups of patients before and after treatment were compared.Result:Compared with before treatment,the neurological function scores and the levels of various inflammatory factors of the two groups of patients were decreased after treatment,and the reduction amplitude of the two groups of patients was compared,indicating that the reduction amplitude of experimental group was larger;the total effective rate of treatment of the two groups of patients was compared,indicating that the experimental group was higher;a comparison of the total incidence of adverse reactions between the two groups of patients,indicating that the experimental group was lower,the differences were statistically significant(P<0.05).Conclusion:The use of Aspirin for emergency treatment of patients with thrombotic cerebral infarction has a positive effect.It can effectively alleviate the clinical symptoms of patients,improve their neurological function,reduce the inflammatory response of patients,and have high drug safety and fewer adverse reactions in patients.It is worthwhile widely used in clinic.

关 键 词：神经功能 不良反应 血栓性脑梗死 炎症因子 阿司匹林 急诊治疗 

分 类 号：R743.3[医药卫生—神经病学与精神病学]