聚桂醇联合微波热消融治疗5〜6型浆膜下子宫肌瘤的疗效观察  

作　　者：吕祝英 雷志锴[1] 楼军[1] 陈龙 韩琳霞 

机构地区：[1]杭州市肿瘤医院,310002

出　　处：《浙江临床医学》2021年第11期1589-1591,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探讨经皮超声引导下聚桂醇注射联合微波热消融治疗5〜6型浆膜下肌瘤的安全性、可行性及其临床应用价值方法对5〜6型、最大直径≥5 cm的5例症状性浆膜下肌瘤患者行经皮超声引导下聚桂醇注射硬化治疗联合微波热消融治疗,术后用超声造影评估消融范围,观察并发症等情况。术后1、3个月进行随访及疗效评估结果5例患者术后即刻超声造影显示瘤体内无造影剂灌注,呈“空洞征”改变,所有患者均未发生明显的并发症。消融前肌瘤体积为(111.49±72.32)cm^(3),治疗后3个月肌瘤的平均体积为(31.57±20.72)cm^(3),平均缩小率为70.81%,症状严重程度评分(SSS)从术前的(42.87±11.13)分降至(25.62±6.77)分结论经皮超声引导下聚桂醇联合微波热消融治疗浆膜下子宫肌瘤短期疗效显著,且避免微波消融治疗的风险,是一种很有前景的治疗方法。Objective To investigate the safety,feasibility and clinical value of percutaneous ultrasound guided lauromacrogol injection combined with microwave thermal ablation in the treatment of type 5〜6 subserosal hysteromyoma,and to explore a new method for the treatment of subscrosal hysteromyoma.Methods Five patients with FIG05〜6 type and the maximum diameter>5 cm were treated with percutaneous ultrasonography guided lauromacrogol injection combined with microwave themial ablation.The ablation range was evaluated by CEUS after therapy and complications were observed.Follow-up and efficacy evaluation were performed at 1 and 3 months after therapy.Results 5 patients immediately after the therapy showed no contrast agent perfusion in the tumor body,showing the change of"cavity sign",no obvious complications.The volume of fibroids before ablation was(111.49±72.32)cm^(3),and the mean volume of fibroids 3 months after treatment was(31.57±20.72)cm^(3),and the mean reduction rate was 70.81%.The symptom severity score(SSS)decreased from(42.87±11.13)to(25.62±6.77).Conclusion Percutaneous ultrasound guided lauromacrogol combined with microwave thermal ablation has a significant short-term efficacy in the treatment of subserosal hysteromyoma,and avoids the risk of microwave ablation.It is a promising treatment method.

关 键 词：聚桂醇 微波消融 浆膜下子宫肌瘤 

分 类 号：R73[医药卫生—肿瘤]