乳腺癌根治术后一期乳房再造对青年乳腺癌患者生存质量的影响因素分析  

Analysis of influencing factors of quality of life in young patients with immediate breast reconstruction after radical mastectomy

作　　者：马晓霞[1] 刘小娜[1] 史博慧 Ma Xiaoxia;Liu Xiaona;Shi Bohui(Department of Breast Surgery,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)

机构地区：[1]西安交通大学第一附属医院乳腺外科,西安710061

出　　处：《中国医学前沿杂志（电子版）》2021年第11期129-132,共4页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

摘　　要：目的探讨乳腺癌根治术后一期乳房再造对青年乳腺癌患者生存质量的影响因素。方法选取2018年1月至2020年10月于西安交通大学第一附属医院就诊的乳腺癌根治术后行一期乳房再造的85例青年乳腺癌患者为研究对象,采用乳腺癌生存质量特异量表(quality of life questionnaire-breast cancer module 23,QLQ-BR23)评估患者手术前后生存质量,并筛选患者生存质量的影响因素。结果85例青年乳腺癌患者术后3个月QLQ-BR23的身体形象、性乐趣、未来展望、乳房症状维度评分和总分均显著高于术前(均P<0.05)。大专及以上文化程度、家庭人均月收入>8000元、已婚、肿瘤分期为Ⅰ期、无术后放疗和/或化疗、高希望水平患者术后3个月QLQ-BR23总分分别显著高于小学及以下文化程度、家庭人均月收入<4000元、未婚/离异/丧偶、肿瘤分期为Ⅲ期、术后放疗和/或化疗、低希望水平者(均P<0.05)。多元线性回归分析结果表明,家庭人均月收入、肿瘤分期、希望水平均为青年乳腺癌患者术后3个月QLQ-BR23总分的独立影响因素(均P<0.05)。结论乳腺癌根治术后行一期乳房再造的青年乳腺癌患者术后生存质量较术前显著提高,经济状况、肿瘤分期、希望水平是此类患者术后生存质量的独立影响因素。Objective To analyze the influencing factors of quality of life in young patients with immediate breast reconstruction after radical mastectomy.Method Eighty-five young patients with immediate breast reconstruction after radical mastectomy in the First Affiliated Hospital of Xi’an Jiaotong University from January 2018 to October 2020 were enrolled for the study.The quality of life questionnaire-breast cancer module 23(QLQ-BR23)was used to assess the quality of life before and after operation and to screen the influencing factors of patients’life quality.Result The scores of body image,sexual pleasure,future prospects and breast symptoms of QLQ-BR23 and the total score at 3 months of 85 young patients with breast cancer after operation were significantly higher than those before operation(all P<0.05).The total score of QLQ-BR23 in young breast cancer patients with junior college education or above,family per capita monthly income>8000 yuan,married,tumor stageⅠ,no postoperative radiotherapy and/or chemotherapy,and high level of hope at 3 months after operation were significantly higher than those of patients with primary school education or below,family per capita monthly income<4000 yuan,unmarried or divorced or widowed,tumor stageⅢ,posto perative radiotherapy and/or chemotherapy,and low level of hope(all P<0.05).Multiple linear regression analysis showed that family per capita monthly income,tumor stage and hope level were the independent influencing factors of the total score of QLQ-BR23 in young breast cancer patients after operation(all P<0.05).Conclusion The quality of life of young patients with immediate breast reconstruction after radical mastectomy are significantly improved compared with before operation.Economic status,tumor stage and hope level are the independent influencing factors of the quality of life of patients after operation.

关 键 词：乳腺癌 生存质量 青年 乳房再造术 

分 类 号：R737.9[医药卫生—肿瘤]