闽南地区儿童实体肿瘤单中心研究  

Single-center study of children′s solid tumors in southern Fujian

作　　者：郭碧赟[1] 王玥[1] 温红[1] 连珠兰 胡洋帆 白海涛[1] GUO Biyun;WANG Yue;WEN Hong;LIAN Zhulan;HU Yangfan;BAI Haitao(Department of Pediatrics,the First Affiliated Hospital of Xiamen University,Pediatric Key Laboratory of Xiamen,Institute of Pediatrics,School of Medicine,Xiamen University.Xiamen 361003,China)

机构地区：[1]厦门大学附属第一医院儿科,厦门市儿科重点实验室,厦门大学医学院儿童医学研究所,厦门361003

出　　处：《中国小儿血液与肿瘤杂志》2021年第5期294-297,309,共5页Journal of China Pediatric Blood and Cancer

摘　　要：目的了解2015—2019年我院儿童实体肿瘤收治情况,为儿童实体肿瘤的防控诊治提供参考依据。方法对2015年1月—2019年12月五年间我院14周岁以下467例新发儿童实体肿瘤患者病历进行统计分析。结果467例儿童实体肿瘤患者初次就诊科室各异,儿外科共收治205例,占43.9%,其次是儿内科98例,占21.0%;男性238例,女性229例,男女之比为1.04∶1;0~3岁病例数占比最高为52.9%,11~14岁年龄组最低为9.0%;手术/活检率99.1%;病理诊断率100%;良性肿瘤353例,占比75.6%,恶性肿瘤93例,占比19.9%,交界性21例,占比4.5%;良性肿瘤发病顺序为血管瘤、钙化上皮瘤、错构瘤等,恶性肿瘤则为恶性畸胎瘤、视网膜母细胞瘤、中枢神经系统和其他颅内和脊髓内肿瘤、淋巴瘤和网状内皮细胞肿瘤等;恶性肿瘤基因检测率达到31.2%(29/93)。结论儿童实体肿瘤有自己的年龄及种类特点,发病率不容小觑,随着诊断技术的进步和治疗手段的改善,我们更需加强多学科合作使儿童实体肿瘤的防控得到进一步的落实。Objective To understand the admission and treatment of children′s solid tumors in our hospital from 2015 to 2019,so as to provide references for the prevention and treatment of children′s solid tumors.Methods The medical records of 467 newly diagnosed children with solid tumors under the age of 14 in our hospital from January 2015 to December 2019 were analyzed.Results 467 cases of children with solid tumors have different initial departments.A total of 205 cases were treated in pediatric surgery department,accounting for 43.9%,followed by 98 cases in pediatric internal medicine department,accounting for 21.0%.There were 238 males and 229 females,with a male to female ratio of 1.04∶1.The highest proportion of cases was 0~3 years old group,accounting for 52.9%,and the lowest was 11~14 years old group,accounting for 9.0%.Surgery/biopsy operation rate was 99.1%;pathology diagnosis rate was 100%;353 cases of benign tumors,accounting for 75.6%,93 cases of malignant tumors,accounting for 19.9%,and 21 cases of borderline tumors,accounting for 4.5%.The order of benign tumors is hemangioma,calcified epithelioma,hamartoma,etc.,and the malignant tumors are malignant teratoma,retinoblastoma,central nervous system and other intracranial and intraspinal tumors,lymphoma and reticular endothelial cells Tumor,etc.;The genetic detection rate of malignant tumors reached 31.2%(29/93).Conclusions Children′s solid tumors have their own characteristics of age and type,and the incidence rate should not be underestimated.With the advancement of diagnostic technology and the improvement of treatment methods,we need to strengthen multidisciplinary cooperation so that the prevention and control of solid tumors in children can be further implemented.

关 键 词：儿童 实体肿瘤 

分 类 号：R73[医药卫生—肿瘤]