卵巢癌患者中医证型与血小板指标的相关性研究  

A study on the relation between TCM syndrome types and platelet of ovarian cancer patients

作　　者：刘欣悦 张宁苏[1] 李夏平[2] Liu Xinyue

机构地区：[1]辽宁中医药大学,辽宁沈阳110847 [2]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《中医临床研究》2021年第26期104-106,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:研究卵巢癌患者中医证型的分布规律及其与血小板之间的关系。方法:采用回顾性分析的方法,收集56例卵巢癌患者的住院资料,使用k-均值聚类分析将其分为气滞血瘀型、痰湿蕴结型、肝肾阴虚型和气血两虚型,并通过单因素ANOVA分析和二元Logistic回归分析比较血小板与卵巢癌患者的中医证型的关系。结果:(1)56例卵巢癌患者中,有气滞血瘀型24例;痰湿蕴结型13例;肝肾阴虚型11例;气血两虚型8例。(2)相比于痰湿蕴结型、肝肾阴虚型和气血两虚型,气滞血瘀型与血小板指标升高存在明显的相关性(P<0.05)。结论:卵巢癌患者以气滞血瘀型多见,在中医治疗中应注意疏肝行气、活血化瘀;并且该型患者多存在血小板升高,血小板指标作对于判断卵巢癌患者的证型存在一定意义,对指导中医药辨证论治改善气滞血瘀型卵巢癌患者的凝血功能异常有一定的帮助。Objective:To study the distribution of TCM syndrome types in patients with ovarian cancer and their relationship with platelets.Methods:The hospitalization data of 56 cases was collected and retrospectively analyzed.The TCM syndrome types of patients with ovarian cancer were divided into the Qi(气)stagnation and blood stasis type,the phlegm-dampness accumulation type,the Yin(阴)deficiency of liver and kidney type,and the deficiency of Qi and blood type.The relationship between platelets and TCM syndrome types was compared by single-factor ANOVA analysis and binary logistic regression analysis.Results:Among 56 cases,there were 24 cases with the Qi stagnation and blood stasis type,13 cases with the phlegm-dampness accumulation type,11 cases with the Yin deficiency of liver and kidney type,and 8 cases with the deficiency of Qi and blood type.Compared with the other three TCM syndrome types,there was a significant correlation between the Qi stagnation and blood stasis type and the increase of PLT indicators(P<0.05).Conclusion:The Qi stagnation and blood stasis type are more common in ovarian cancer patients than other types.The therapy of dispersing stagnated liver Qi,and promoting blood circulation to remove blood stasis should be applied in clinic.In addition,platelets in patients with this type often has elevated,which has a certain significance in judging the TCM syndrome type,and it is helpful to guide TCM syndrome differentiation and treatment to improve the abnormal blood coagulation function of patients with the Qi stagnation and blood stasis type ovarian cancer.

关 键 词：卵巢癌 中医证型 血小板 

分 类 号：R73[医药卫生—肿瘤]