白光内镜下和ME-NBI下的早期胃癌病灶的形态学特征及早期胃癌的危险因素  

Morphological Features of Early Gastric Cancer Lesions Under White Light Endoscopy and ME-NBI and Risk Factors For Early Gastric Cancer

作　　者：陈旭 王贺 邹启云[1] CHEN Xu;WANG He;ZOU Qiyun(Henan Cancer Hospital,Zhengzhou,450000)

机构地区：[1]河南省肿瘤医院,450000

出　　处：《实用癌症杂志》2021年第11期1841-1843,1850,共4页The Practical Journal of Cancer

摘　　要：目的探究白光内镜下和癌前病变采用放大内镜(ME)-内镜窄带成像(NBI)下的早期胃癌(EGC)病灶的形态学特征及早期胃癌的危险因素。方法选择早期胃癌和癌前病变的患者160例,低级别上皮内瘤变(LGIN)组,高级别上皮内瘤变(HGIN)组,EGC组。分析白光内镜下早期胃癌病灶的形态学特征和ME-NBI下的特征性表现,并进一步分析影响早期胃癌患者的危险因素。结果术后病理结果显示,181个病灶中存在106个LGIN、28个HGIN、41个HGC。白光内镜下EGC病灶形态学特征主要表现为Ⅱc型,占48.78%(20/41)。ME-NBI下EGC病灶形态学特征主要表现为病变和周围粘膜间具有边界线,且表面微结构与微血管均不规则。Logistic比例风险回归模型分析结果显示,幽门螺杆菌感染、病灶大小、胃粘膜萎缩均可作为影响早期胃癌患者的危险因素。结论白光内镜下EGC病灶形态学特征主要表现为Ⅱc型,ME-NBI下EGC病灶形态学特征主要表现为病变和周围粘膜间具有边界线,且表面微结构与微血管均不规则,幽门螺杆菌感染、病灶大小、胃粘膜萎缩均可作为影响早期胃癌患者的危险因素。Objective To explore the morphological characteristics and risk factors of early gastric cancer(EGC)lesions under white light endoscopy(ME)and endoscopic narrow band imaging(NBI)and early gastric cancer.Methods 160 patients with early gastric cancer and precancerous lesions were selected,low grade intraepithelial neoplasia(LGIN)group,High grade intraepithelial neoplasia(HGIN)group,Group EGC.Analysis of morphological features and ME-NBI features of early gastric cancer lesions under white light endoscopy were conducted,and further analyze the risk factors affecting early gastric cancer patients.Results Postoperative pathology showed that,There were 106 LGIN、28 HGIN、41 HGC in 181 lesions.The morphological features of EGC lesions were IIc type,It accounted for 48.78%(20/41).The morphological features of EGC lesions in the ME-NBI were the boundary between the lesion and the surrounding mucosa,The surface microstructure and microvessel were irregular.Logistic proportional risk regression model,Helicobacter pylori infection,lesion size and gastric mucosal atrophy can be used as risk factors for early gastric cancer patients.Conclusion The morphological features of EGC lesions under white light endoscopy are mainly IIc type.The morphological features EGC the lesions under ME-NBI are mainly the boundary line between the lesions and the surrounding mucosa,and the surface microstructures and microvessels are irregular.h.pylori infection,lesion size,and gastric mucosal atrophy can be used as risk factors for early gastric cancer patients.

关 键 词：早期胃癌 白光内镜 ME-NBI 幽门螺杆菌 

分 类 号：R735.2[医药卫生—肿瘤]