微波消融治疗小肝癌的效果分析  

Analysis of the effect of microwave ablation in the treatment of small liver cancer

作　　者：程笑[1] 黄静[1] 李文飞 钟涛[1] 蔡丽娟 李晖[1] 郭亚兵[1] 陈锦章[1] Cheng Xiao;Huang Jing;Li Wenfei;Zhong Tao;Cai Lijuan;Li Hui;Guo Yabing;Chen Jinzhang(Department of Infectious Diseases,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Health Management Center,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China)

机构地区：[1]南方医科大学南方医院感染内科,广州510515 [2]南方医科大学南方医院健康管理科,广州510515

出　　处：《中华肝脏病杂志》2021年第11期1059-1062,共4页Chinese Journal of Hepatology

摘　　要：目的探讨微波消融治疗早期小肝癌(≤3 cm)的临床效果。方法回顾性搜集2016年11月至2018年11月行微波消融治疗的103例小肝癌(肿瘤数目不超过3个, 肿瘤最大直径不超过3 cm)患者, 观察手术后病灶残留率、术后1年复发率和手术并发症。按肿瘤大小分为< 2 cm和≥2 cm组, 按肿瘤数目分为单个和2~3个病灶组, 对比分析各组治疗效果。结果小肝癌微波消融治疗术后肿瘤残留率、1年复发率分别为11.7%、35.0%, 消融后综合征发生率为52.4%, 无严重不良事件发生。对比< 2 cm肿瘤, ≥2 cm患者术后残留率更高(χ2 = 7.651, P = 0.006), 单个肿瘤的1年复发率较多结节肿瘤更低(χ2 = 10.125, P = 0.001)。结论微波消融是早期小肝癌安全有效的治疗方法, 对单发小结节(< 2 cm)肿瘤效果更好。Objective To explore the clinical effect of microwave ablation in the treatment of early small liver cancer(≤3 cm).Methods 103 cases with small liver cancer(tumor number<3 and maximum tumor diameter<3 cm)who underwent microwave ablation from November 2016 to November 2018 were retrospectively collected.The rate of residual lesions,recurrence rate one-year after the operation,and surgical complications were observed and grouped according to tumor size(<2 cm and≥2 cm group)and tumor numbers(solitary and 2〜3 lesion groups).The therapeutic effects of each group were compared and analyzed.Results The tumor residual rate and one-year recurrence rate of small liver cancer after microwave ablation were 11.7%and 35.0%,respectively.The post-ablation syndrome incidence rate was 52.4%,with no serious adverse events.Compared with tumors<2 cm,patients with≥2 cm had a higher postoperative residual rate(X^(2)=7.651,P=0.006),and the one-year recurrence rate of more solitary nodular tumors was lower(X^(2)=10.125,P=0.001).Conclusion Microwave ablation is a safe and effective treatment for early small liver cancer,and it is more effective for small solitary nodules(<2 cm).

关 键 词：肝细胞癌 疗效 微波消融 

分 类 号：R735.7[医药卫生—肿瘤]