不同途径腹腔镜前列腺癌根治术治疗前列腺癌的效果和安全性分析  

Efficacy and safety analysis of different approaches of laparoscopic radical prostatectomy in the treatment of prostate cancer

作　　者：周昌东[1] 田玉新[1] 杨新平[1] 张奇夫 ZHOU Chang-dong;TIAN Yu-xin;YANG Xin-ping;ZHANG Qi-fu(Department of Urology,Jilin Cancer Hospital,Jijin Province,Changchun,130012,China)

机构地区：[1]吉林省肿瘤医院泌尿外科,吉林长春130012

出　　处：《中国当代医药》2021年第33期101-103,107,共4页China Modern Medicine

摘　　要：目的分析和探讨不同途径腹腔镜前列腺癌根治术治疗前列腺癌的效果和安全性。方法选取2017年9月至2019年9月吉林省肿瘤医院泌尿外科收治的66例前列腺癌患者作为研究对象,采用随机数字表法将其分为对照组与观察组,每组各33例。对照组患者采用经腹腔途径腹腔镜前列腺癌根治术,观察组患者采用经腹膜外途径腹腔镜前列腺癌根治术。比较两组患者的手术指标、并发症发生情况、术后切缘阳性率以及治疗总有效率。结果观察组患者的手术时间、术后尿管留置时间、术后恢复流食时间、术后引流管拔出时间以及住院时间均短于对照组,差异有统计学意义(P<0.05);两组患者的术中出血量比较,差异无统计学意义(P>0.05)。观察组患者的并发症总发生率低于对照组,差异有统计学意义(P<0.05)。两组患者的术后切缘阳性率比较,差异无统计学意义(P>0.05)。观察组患者的治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论经腹膜外途径腹腔镜前列腺癌根治术治疗前列腺癌的效果显著,值得在临床进行实施和开展。Objective To analyze and explore the effect and safety of laparoscopic radical prostatectomy in the treatment of prostate cancer.Methods A total of 66 patients with prostate cancer in the Department of Urology of Jilin Cancer Hospital from September 2017 to September 2019 were selected as the research objects.They were divided into the control group and the observation group by random number table method,with 33 cases in each group.The patients in the control group were treated with laparoscopic radical prostatectomy via abdominal approach,and the patients in the observation group were treated with laparoscopic radical prostatectomy via extraperitoneal approach.Surgical indicators,complications,positive rate of surgical margin and total effective rate were compared between the two groups.Results The operation time,postoperative catheter indwelling time,postoperative fluid feeding time,postoperative drainage tube removal time and hospital stay in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in intraoperative blood loss between the two groups(P>0.05).The total incidence of complications in observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the positive rate of surgical margin between the two groups(P>0.05).The total effective rate of observation group was higher than that of control group,and the difference was statistically significant(P<0.05).Conclusion The effect of extraperitoneal laparoscopic radical prostatectomy in the treatment of prostate cancer is remarkable and worthy of clinical implementation and development.

关 键 词：经腹膜外途径腹腔镜前列腺癌根治术 经腹腔途径腹腔镜前列腺癌根治术 前列腺癌 效果 安全性 

分 类 号：R737.25[医药卫生—肿瘤]