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机构地区:[1]Department of Molecular Biosciences,The University of Texas at Austin,Austin,TX 78712,USA
出 处:《Molecular Plant》2021年第9期1430-1432,共3页分子植物(英文版)
基 金:We acknowledge supports from NIH(R01GM100108)and NSF(IOS1656764)to S.S.
摘 要:In eukaryotes,the three-dimensional(3D)structure of the genome plays a critical role in the transcriptional regulation.Even though the 3D structure of the genome is mainly determined by DNA and protein components,increasing evidenee has demonstrated that RNA also occupies a large portion of chromatin and in flue nces genomic architecture(Ramirez-Colmenero et al.,2020;Wierzbicki et al.,2021).Long non-coding RNA(IncRNA)is a class of non-coding RNAs longer than 200 nucleotides but that lacks protein-coding potential.IncRNAs are key regulators of gene expression through their capacity to harbor regulatory proteins and to establish molecular interactions.
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