提高戒断疫苗免疫学效果的策略及验证手段  

The immunological effect optimization method and detection method of withdrawal vaccine

作　　者：刘翠秀 郑鹏 李映波[2] 曾发明[3] LIU Cuixiu;ZHENG Peng;LI Yingbo;ZENG Faming(School of Forensic,Kunming Medical University,Kunming,650500;Institute of Medical Biology,Chinese Academy of Medical Sciences,Peking Union Medical College,Kunming,650118;Criminal Investigation Team of Yunnan Public Security Department,Kunming,650228)

机构地区：[1]昆明医科大学法医学院,昆明650500 [2]中国医学科学院/北京协和医学院医学生物学研究所,昆明650118 [3]云南省公安厅刑侦总队,昆明650228

出　　处：《中国药物依赖性杂志》2021年第4期255-258,共4页Chinese Journal of Drug Dependence

摘　　要：物质滥用或依赖是当今社会亟待解决的重大公共健康卫生问题之一,酒精依赖、香烟过度吸食及毒品滥用等现象威胁着个人健康及家庭和社会的稳定。在众多预防及治疗方法中,戒断疫苗的免疫疗法具有很大发展前景,目前的相关研究已初具成果,但是在疫苗产生的免疫学效果上还存在一些不足和挑战,所以很少有成功进入临床阶段的戒断疫苗。为促进技术交流,有必要对一些优化的戒断疫苗方法进行探讨。以下就提高戒断疫苗免疫学效果的方法及相应验证手段进行综述。Substance abuse or dependence is one of the major public health problems that need to be solved urgently in today′s society.Alcohol dependence,excessive cigarette smoking and drug abuse threaten the stability of individuals,families and society.Among the many prevention and treatment methods,the immunotherapy of withdrawal vaccine has great development prospects.The current related research has yielded initial results,but there are still some shortcomings and challenges in the immunological effect of the vaccine,So few withdrawal vaccines have successfully entered the clinical stage.In order to promote technical exchanges,integration,and progress,it is imperative to discuss some optimized withdrawal vaccine methods.The following is a summary of methods to improve the immunological effects of withdrawal vaccines and corresponding verification methods.

关 键 词：药物成瘾 药物滥用 疫苗 戒断治疗 免疫疗法 

分 类 号：R749[医药卫生—神经病学与精神病学]