低剂量CT扫描在不同年龄段疑似肺癌患者中的应用  

Application of low-dose CT scanning in suspected lung cancer patients of different ages

作　　者：李赛玉 阙薇薇 LI Saiyu;QUE Weiwei(PCCM,Longyan First Hospital Affiliated to Fujian Medical University,Longyan364000,China)

机构地区：[1]福建医科大学附属龙岩第一医院呼吸与危重症医学科,福建龙岩364000

出　　处：《中国现代医生》2021年第28期92-95,共4页China Modern Doctor

摘　　要：目的探讨低剂量CT(LDCT)扫描在不同年龄段疑似肺癌患者中的应用价值。方法回顾性分析2016年1月至2018年12月我院收治的300例疑似肺癌患者临床资料,依据患者年龄分为低年龄组(≤40岁)184例和高年龄组(>40岁)116例,所有患者均行LDCT扫描检查,以病理检查结果作为“金标准”,分析比较LDCT扫描检查在不同年龄段疑似肺癌患者中的应用价值。结果经病理检查可知,低年龄组184例患者中149例诊断为恶性,占80.98%,35例为良性,占19.02%;高年龄组116例患者中95例诊断为恶性,占81.90%,21例为良性,占18.10%。LDCT扫描检查高年龄组的准确度、灵敏度、良性预测价值高于低年龄组,差异有统计学意义(P<0.05);LDCT扫描检查高年龄组的特异度、恶性预测价值略高于低年龄组,差异无统计学意义(P>0.05);且LDCT扫描检查低年龄组结果与病理检查结果具有理想一致性(Kappa=0.508),LDCT扫描检查高年龄组结果与病理检查结果具有极好的一致性(Kappa=0.857)。结论LDCT扫描检查对不同年龄段疑似肺癌患者的鉴别具有较高准确度、灵敏度、良性预测价值,且高年龄患者诊断效果更优,可作为临床诊断肺癌的有效检查方法。Objective To investigate the application value of the low-dose CT(LDCT)scanning in suspected lung cancer patients of different ages.Methods The clinical data of 300 patients with suspected lung cancer who were admitted to our hospital from January 2016 to December 2018 were retrospectively analyzed,and the patients were divided into the lower age group(≤40 years old,n=184)and the higher age group(>40 years old,n=116)according to their age.All patients were given the LDCT scanning examination,and the pathological examination results were taken as the"gold standard"to analyze and compare the application value of the LDCT scanning examination in suspected lung cancer patients of different ages.Results According to the pathological examination,149 patients(80.98%)of the 184 patients in the lower age group were diagnosed as malignant,while 35 patients(19.02%)were benign.Among 116 patients in the higher age group,95 patients(81.90%)were diagnosed as malignant and 21 patients(18.10%)were diagnosed as benign.The accuracy,sensitivity and benign prediction value of the LDCT scanning examination in the higher age group were higher than those in the lower age group,and the differences were statistically significant(P<0.05).The specificity and malignancy prediction value of the LDCT scanning examination in the higher age group were slightly higher than those in the lower age group,and the differences were not statistically significant(P>0.05).The results of the LDCT scanning examination in the lower age group were in ideal agreement with the pathological examination results(Kappa=0.508),and the results of the LDCT scanning examination in the higher age group were in excellent agreement with the pathological examination results(Kappa=0.857).Conclusion The LDCT scanning examination has high accuracy,sensitivity and benign prediction value in the identification of suspected lung cancer patients of different ages,and it is more effective in the diagnosis of older patients,so it can be used as an effective examination method for

关 键 词：疑似肺癌 低剂量CT扫描 鉴别诊断 不同年龄段 

分 类 号：R734.2[医药卫生—肿瘤]