碳量子点镶嵌二氧化钛纳米管阵列的光电化学传感器构建及5-羟色胺的快速分析  

Fabrication of Carbon Quantum Dots Decorated TiO_(2) Nanotube Arrays for Photoelectrochemical Determination of 5-Hydroxytryptamine

作　　者：姚梦婷 齐凯丽 梅正方 陈荣生 YAO Meng-Ting;QI Kai-Li;MEI Zheng-Fang;CHEN Rong-Sheng(State Key Laboratory of Refractories and Metallurgy,Institute of Advanced Materials and Nanotechnology,School of Chemistry and Chemical Engineering,Wuhan University of Science and Technology,Wuhan 430081,China)

机构地区：[1]武汉科技大学化学与化工学院,先进材料与纳米技术研究院,省部共建耐火材料与冶金国家重点实验室,武汉430081

出　　处：《分析化学》2021年第12期2005-2014,共10页Chinese Journal of Analytical Chemistry

基　　金：国家重点研发计划项目(No.2020YFC1909702)资助。

摘　　要：基于碳量子点镶嵌的二氧化钛纳米管阵列(TiO_(2) NTAs/CQDs)构建了一种新型光电化学(PEC)传感器。采用电化学阳极氧化法制备形貌规整的自支撑二氧化钛纳米管阵列(TiO_(2) NTAs),纳米管内径约80 nm、长度约8μm,采用电化学氧化法制备CQDs,直径3~9 nm,然后通过水热处理将CQDs修饰到TiO_(2) NTAs上,构建了PEC传感器用于5-羟色胺(5-HT)的检测。电镜图显示,CQDs镶嵌在TiO_(2)纳米管内外壁,分布均匀。CQDs的修饰可有效减小材料的禁带宽度,增强其在可见光下的响应,并减少光生电子-空穴的复合率,提升PEC检测的光电流,有效改善TiO_(2) NTAs的导电性。研究结果表明,在可见光下,TiO_(2) NTAs/CQDs对5-HT具有良好的光电流响应,在20~300μmol/L浓度范围内呈良好的线性关系,检出限为11.50μmol/L(S/N=3)。此PEC传感器具有良好的抗干扰性和稳定性,可应用于人血清中5-HT的测定。A novel photoelectrochemical(PEC)sensor was constructed based on carbon quantum dots decorated titanium dioxide nanotube arrays(TiO_(2)NTAs/CQDs).Highly ordered self-supporting titanium dioxide nanotube arrays(TiO_(2)NTAs)were prepared on the surface of a titanium foil by electrochemical anodization.The diameter and the length of TiO_(2)nanotube were around 80 nm and 8μm,respectively.CQDs were prepared by electrochemical anodization of a graphite electrode,with a diameter of 3-9 nm.Uniformly distributed CQDs were decorated on the inner walls of TiO_(2)NTAs by hydrothermal treatment,examined by TEM observation.CQDs could effectively reduce the band gap of TiO_(2)NTAs and enhanced its response under visible light.CQDs were electron acceptors that could promote the separation of photo-generated electron-hole pairs.The conductance of TiO_(2)NTAs was also enhanced by CQDs decoration.Under visible light,TiO_(2)NTAs/CQDs exhibited excellent PEC response toward 5-hydroxytryptamine(5-HT),with a linear range of 20-300μmol/L and a detection limit of 11.5μmol/L(S/N=3).Moreover,the PEC sensor showed good selectivity and stability for determination of 5-HT and was successfully applied to determination of 5-HT in human serum.

关 键 词：光电化学传感器 二氧化钛纳米管阵列 碳量子点 可见光响应 5-羟色胺 

分 类 号：R741[医药卫生—神经病学与精神病学] O657.1[医药卫生—临床医学]