急性缺血性脑卒中患者血清胆固醇水平与颅内外动脉狭窄程度的关系分析  

Analysis of the relationship between the serum cholesterol level and the degree of intracranial and extracranial artery stenosis in patients with acute ischemic stroke

作　　者：宋璞[1] Song Pu(Department of Neurology,The Central Hospital of Xuzhou City,Jiangsu Xuzhou 221000)

机构地区：[1]徐州市中心医院神经内科,江苏徐州221000

出　　处：《中国社区医师》2021年第34期109-110,共2页Chinese Community Doctors

摘　　要：目的:分析急性缺血性脑卒中患者血清胆固醇水平与颅内外动脉狭窄程度的关系。方法:2017年1月-2019年12月收治急性缺血性脑卒中患者118例,作为观察组;然后根据患者入院后进行的颅脑CTA或MRA检查结果及颈部超声检查结果进行分组。A组18例血管正常;B组30例血管闭塞;C组70例血管狭窄。同时选取同期进行健康体检者118例。比较各组血脂水平。结果:A组LDL-C水平明显低于B组、C组,差异有统计学意义(P<0.05);A组、B组、C组TC、TG、HDL-C及Lp(a)水平比较,差异无统计学意义(P>0.05)。观察组TG、Lp(a)水平高于对照组,HDL-C水平低于对照组,差异有统计学意义(P<0.05);观察组和对照组TC、LDL-C水平比较,差异无统计学意义(P>0.05)。结论:检测急性缺血性脑卒中患者血清胆固醇水平,有助于临床医生了解患者病情,判断血管狭窄严重程度,利于为患者后续治疗提供依据,以制定最佳方案。Objective:To analyze the relationship between the serum cholesterol level and the degree of cardiovascular and cerebrovascular stenosis in patients with acute ischemic stroke.Methods:From January 2017 to December 2019,118 patients with acute ischemic stroke were selected as the observation group.The patients were grouped according to the results of brain CTA or MRA examinations and neck ultrasound examinations after admission.18 cases of the group A had normal blood vessels.30 cases of the group B had vascular occlusion.70 cases of the group C had vascular stenosis.At the same time,118 patients who underwent physical examination during the same period were selected.We compared the serum lipid levels of each group.Results:The level of LDL-C in the group A was significantly lower than that of the group B and the group C,the difference was statistically significant(P<0.05).There was no statistically significant difference in the levels of TC,TG,HDL-C and Lp(a)among the three groups(P>0.05).The levels of TG and Lp(a)in the observation group were higher than those in the control group,and the levels of HDL-C were lower than those in the control group,the differences were statistically significant(P<0.05).There was no statistically significant difference in the levels of TC and LDL-C between the two groups(P>0.05).Conclusion:The detection of serum cholesterol levels in patients with acute ischemic stroke can help clinicians understand the patient's condition,determine the severity of the patient's vascular stenosis,and make the best plan for the patient's subsequent treatment.

关 键 词：急性缺血性脑卒中 血清胆固醇水平 心脑血管狭窄程度 

分 类 号：R743.3[医药卫生—神经病学与精神病学]