表现为良性肿瘤的干痛型腹膜恶性间皮瘤1例  

The dry painful type malignant peritoneal mesothelioma presented as benign tumor:a case report

作　　者：杨远园 付瑞敏 王进京 文坤明 YANG Yuanyuan;FU Ruimin;WANG Jinjing;WEN Kunming(Department of Gastrointestinal Surgery,The Affiliated Hospital of Zunyi Medical University,Zunyi,Guizhou 563000,China;Department of Pathology,The Affiliated Hospital of Zunyi Medical University,Zunyi,Guizhou 563000,China)

机构地区：[1]遵义医科大学附属医院胃肠外科,贵州遵义563000 [2]遵义医科大学附属医院病理科,贵州遵义563000

出　　处：《安徽医药》2021年第12期2391-2393,I0002,共4页Anhui Medical and Pharmaceutical Journal

基　　金：国家自然科学基金项目(81560404)。

摘　　要：目的总结1例表现为良性肿瘤的干痛型腹膜恶性间皮瘤治疗过程及预后分析。方法回顾性分析遵义医科大学附属医院胃肠外科,在2019年3月收治的1例病人,术前影像学及术中均考虑良性肿瘤,将肿瘤完整切除,术后病理结果为恶性腹膜间皮瘤的病例资料,对病人的治疗过程及预后进行分析。结果48岁女因“上腹疼痛伴饱胀不适4月,发现上腹部包块1月”入院。手术将肿瘤完整切除,术后行“培美曲塞+顺铂+贝伐珠单抗”三者联合辅助治疗,每月1次,共行10个周期,现已经随访了1.5年,行全腹CT平扫+增强,未见肿瘤复发,体质量较术前增加13 kg,预后良好。结论表现为良性肿瘤的干痛型腹膜恶性间皮瘤预后良好。Objective To summarize the treatment process and prognosis of a case of the dry painful type peritoneal malignant me-sothelioma presented as benign tumor.Methods One patient who admitted to the Department of Gastrointestinal surgery of the affiliat-ed Hospital of Zunyi Medical University in March 2019 was retrospectively analyzed.The benign tumor was considered in both preoper-ative and intraoperative imaging,and the tumor was removed completely,the postoperative pathological result was malignant peritoneal mesothelioma.The treatment process and prognosis of the patients were analyzed.Results A 48 year old female was admitted to hospi-tal because of epigastric pain with fullness discomfort for 4 months and epigastric mass for 1 month.The tumor was resected complete-ly,and the patient was treated with pemetrexed+cisplatin+bevacizumab after the operation,once a month for 10 cycles.The patient has been followed up for 1.5 years.The whole abdominal CT+enhanced scan showed no tumor recurrence.The body mass increased by 13 kg compared with that before operation and achieve a good prognosis.Conclusion The dry painful type malignant peritoneal me-sothelioma presented as benign tumor which has a good prognosis.

关 键 词：间皮瘤 腹痛 石棉 恶性腹膜间皮瘤 干痛型 手术 辅助治疗 预后 

分 类 号：R735.5[医药卫生—肿瘤]