苯扎氯铵稀释液预防宫颈癌术后留置尿管相关性尿路感染的效果  

Effect of Benzalkonium Chloride Diluent in Preventing Indwelling Catheter-related Urinary Tract Infection after Cervical Cancer Surgery

作　　者：褚国城[1] CHU Guocheng(The Second Affiliated Hospital of Fujian Medical University,Quanzhou 362000,China)

机构地区：[1]福建医科大学附属第二医院,福建泉州362000

出　　处：《中外医学研究》2021年第32期104-106,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨苯扎氯铵稀释液预防宫颈癌术后留置尿管相关性尿路感染的效果。方法:将2019年1月-2020年5月本院132例接受宫颈癌根治术的住院患者随机分为对照组(65例)和观察组(67例)。对照组术后接受常规碘伏液尿管护理,2次/d,观察组在常规尿管护理的基础上,给予苯扎氯铵稀释液冲洗尿道口、导尿管及会阴部皮肤黏膜,2次/d,比较两种会阴护理方法对尿白细胞、细菌培养及尿路感染发生率的影响。结果:观察组术前尿白细胞计数水平与对照组相似,差异无统计学意义(t=0.919,P=0.180),但术后3、7 d观察组尿白细胞计数水平均明显低于对照组,差异有统计学意义(P<0.05)。观察组有3例患者为无症状性尿路感染,2例为症状性尿路感染,而对照组有10例为无症状性尿路感染,4例为症状性尿路感染。观察组尿路感染率为7.46%(5/67),而对照组为21.54%(14/65),差异有统计学意义(χ^(2)=5.327,P=0.021)。结论:与碘伏液相比,采用0.01%苯扎氯铵稀释液进行会阴护理,可以有效降低宫颈癌术后患者留置尿管相关尿路感染的发生率,对维持会阴卫生具有良好的作用。Objective:To investigate the effect of Benzalkonium Chloride Diluent to prevent indwelling catheter-related urinary tract infection (ICUI) after cervical cancer surgery (CCS).Method:A total of 132 inpatients undergoing CCS from January 2019 to May 2020 in our hospital were randomly divided into a control group (65 cases) and an observation group (67 cases).Patients in the control group received Iodophor for routine urinary catheter care twice a day after the operation.On the basis of routine urinary catheter care,patients in the observation group were given Benzalkonium Chloride Diluent to flush the urethral orifice,catheter and perineal skin and mucous membranes twice daily.The effects of two perineal care methods on urinary white blood cells (UWBC),bacterial culture (BC) and the incidence of ICUI were compared.Result:The preoperative UWBC counts of the observation group were similar to those of the control group,and the difference was not statistically significant (t=0.919,P=0.180),but the UWBC counts of the observation group were significantly lower than those of the control group at 3 and 7 days after operation,and the differences were statistically significant (P<0.05).In the observation group,3 patients had asymptomatic ICUI and 2 patients had symptomatic ICUI,while in the control group,10 patients had asymptomatic ICUI and 4 patients had symptomatic ICUI.The rate of ICUI in the observation group was 7.46% (5/67),while that in the control group was 21.54% (14/65),and the difference was statistically significant (χ^(2)=5.327,P=0.021).Conclusion:Compared with Iodophor,0.01% Benzalkonium Chloride Diluent can effectively reduce the incidence of ICUI in patients after CCS,and has a good effect on maintaining perineal hygiene.

关 键 词：苯扎氯铵 尿路感染 留置尿管 会阴护理 

分 类 号：R737.33[医药卫生—肿瘤] R691.3[医药卫生—临床医学]