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作 者:Kejal D Gandhi Pahnwat Tonya Taweesedt Munish Sharma Salim Surani
机构地区:[1]Department of Internal Medicine,Medstar Washington Hospital Center/Georgetown University,Washigton,DC 20010,United States [2]Department of Medicine,Corpus Christi Medical Center,Corpus Christi,TX 78412,United States [3]Department of Medicine,Texas A&M University,Bryan,TX 78413,United States [4]Department of Anesthesiology,Mayo Clinic,Rochester,MN 55905,United States
出 处:《World Journal of Hepatology》2021年第11期1699-1706,共8页世界肝病学杂志(英文版)(电子版)
摘 要:Hepatopulmonary syndrome(HPS)is characterized by defects in oxygenation caused by intra-pulmonary vasodilation occurring because of chronic liver disease,portal hypertension,or congenital portosystemic shunts.Clinical implications of portal hypertension are very well-known,however,awareness of its effect on multiple organs such as the lungs are less known.The presence of HPS in chronic liver disease is associated with increased mortality.Medical therapies available for HPS have not been proven effective and definitive treatment for HPS is mainly liver transplantation(LT).LT improves mortality for patients with HPS drastically.This article provides a review on the definition,clinical presentation,diagnosis,and management of HPS.
关 键 词:Hepatopulmonary syndrome Chronic liver disease HYPOXEMIA Intrapulmonary vasodilatation Liver failure
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