Clinical presentation of gastric Burkitt lymphoma presenting with paraplegia and acute pancreatitis:A case report  

作　　者：Ying Lin Yu-Hang Pan Ming-Kai Li Xiao-Dan Zong Xue-Mei Pan Shu-Yan Tan Yun-Wei Guo 

机构地区：[1]Department of Gastroenterology,The Third Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510630,Guangdong Province,China [2]Department of Pathology,The Third Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510630,Guangdong Province,China

出　　处：《World Journal of Gastroenterology》2021年第45期7844-7854,共11页世界胃肠病学杂志（英文版）

基　　金：The Science and Technology Planning Project of Guangzhou City,No.201803010018.

摘　　要：BACKGROUND The incidence of gastric Burkitt lymphoma(BL),presenting as paraplegia and acute pancreatitis,is extremely low.BL is a great masquerader that presents in varied forms and in atypical locations,and it is prone to misdiagnosis and missed diagnosis.The prognosis of BL remains poor because of the difficulty in early diagnosis and the limited advances in chemotherapy.CASE SUMMARY A 53-year-old man was referred to our hospital from the local county hospital due to abdominal pain for two weeks and weakness in the lower extremities for one day.Magnetic resonance imaging of the abdomen and lumbar spine showed a swollen pancreas and gallbladder,with peripancreatic exudation and liquid collection,indicating acute pancreatitis and acute cholecystitis.Additionally,we observed abnormally thickened lesions of the gastric wall,multiple enlarged retroperitoneal lymph nodes and a well-demarcated,posterolateral extradural mass lesion between T9 and T12,with extension through the spinal foramen and definite bony destruction,suggesting metastasis in gastric malignancy.Subsequent whole-body positron emission tomography/computed tomography examination showed multifocal malignant lesions in the stomach,pancreas,gallbladder,bone,bilateral supraclavicular fossa,anterior mediastinum,bilateral axillary and retroperitoneal lymph nodes.Gastroduodenal endoscopy revealed primary BL with massive involvement of the gastric body and duodenum.The patient refused chemotherapeutic treatment and died one week later due to upper gastrointestinal hemorrhage.Afterward,we reviewed the characteristics of 11 patients with BL involving the stomach,pancreas or spinal cord.CONCLUSION Clinicians should be aware that BL can be the potential cause of acute pancreatitis or a rapidly progressive spinal tumor with accompanying paraplegia.For gastric BL,gastroscopy biopsies and pathology are necessary for a definite diagnosis.

关 键 词：Burkitt lymphoma PARAPLEGIA Acute pancreatitis Case report 

分 类 号：R735.2[医药卫生—肿瘤]