Thoracoscopic resection of a large lower esophageal schwannoma:A case report and review of the literature  

作　　者：Tian-Yi Wang Bian-Li Wang Fu-Rong Wang Meng-Yuan Jing Lu-Dan Zhang De-Kui Zhang 

机构地区：[1]Department of Gastroenterology,Lanzhou University Second Hospital,Lanzhou 730030,Gansu Province,China [2]Department of Pathology,Lanzhou University Second Hospital,Lanzhou 730030,Gansu Province,China [3]Department of Radiology,Lanzhou University Second Hospital,Lanzhou 730030,Gansu Province,China

出　　处：《World Journal of Clinical Cases》2021年第35期11061-11070,共10页世界临床病例杂志

基　　金：Supported by National Natural Science Foundation of China,No.81770525.

摘　　要：BACKGROUND Esophageal schwannomas originating from Schwann cells are extremely rare esophageal tumors.They commonly occur in the upper and middle esophagus but less frequently in the lower esophagus.Herein,we report a rare case of a large lower esophageal schwannoma misdiagnosed as a leiomyoma.We also present a brief literature review on lower esophageal schwannomas.CASE SUMMARY A 62-year-old man presented with severe dysphagia lasting 6 mo.A barium esophagogram showed that the lower esophagus was compressed within approximately 5.5 cm.Endoscopy revealed the presence of a large submucosal protuberant lesion in the esophagus at a distance of 32-38 cm from the incisors.Endoscopic ultrasound findings demonstrated a 4.5 cm×5.0 cm hypoechoic lesion.Chest computed tomography revealed a mass of size approximately 53 mm×39 mm×50 mm.Initial tests revealed features indicative of leiomyoma.After multidisciplinary discussions,the patient underwent a video-assisted thoracoscopic partial esophagectomy.Further investigation involving immunohistochemical examination confirming palisading spindle cells as positive for S100 and Sox10 led to the final diagnosis of a lower esophageal schwannoma.There was no tumor recurrence or metastasis during follow-up.CONCLUSION The final diagnosis of esophageal schwannoma requires histopathological and immunohistochemical examination.The early appropriate surgery favors a remarkable prognosis.

关 键 词：Lower esophagus Esophageal schwannoma Esophageal leiomyoma S100 Sox10 Case report 

分 类 号：R735.1[医药卫生—肿瘤]