Serum vitamin E concentration is negatively associated with body mass index change in girls not boys during adolescence  

作　　者：Xiao-Dong Zang Qing-Hui Hu Xiao-Xu Liu Min Da Zhao-Cong Yang Ji-Rong Qi Xu-Ming Mo 

机构地区：[1]Department of Cardiothoracic Surgery,Children's Hospital of Nanjing Medical University,Jiangdong South No.8 Road,Nanjing 210008,China [2]The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230001,China

出　　处：《World Journal of Pediatrics》2021年第5期517-526,共10页世界儿科杂志（英文版）

基　　金：supported by the China Postdoctoral Science Foundation(2019M651904);the Key Project supported by the Medical Science and Technology Development Foundation,Nanjing Municipality Health Bureau(ZKX19039);the National Key Research and Development Program of China(2017YFC1308105,2016YFC1101001);the National Natural Science Foundation of China(81970265,82000303).

摘　　要：Background Vitamin E is the most abundant lipid-soluble antioxidants present in plasma;however,the relationship between serum vitamin E and change in body mass index(BMI)-for-age Z scores in adolescents has not been well described.Methods This study is a cross-sectional study.Data were analyzed from 4014 adolescents who participated in the National Health and Nutrition Examination Survey.The nutritional status was calculated by BMI Z scores and was classifed into nor-mal weight,overweight,and obese.Multivariable-adjusted logistic regression was used to examine the association between serum vitamin E levels with overweight/obesity.Besides,the interaction effects between potential confounders and vitamin E on obesity were further evaluated.Results After adjusting potential confounders,serum vitamin E levels were negatively associated with overweight/obesity in girls but not in boys.Per standard deviation increment in vitamin E concentrations was associated with a 92%decreased risk of obesity in females.Besides,lower quartiles of serum vitamin E were associated with a higher risk of overweight/obesity in girls.Moreover,the inverse association between serum vitamin E levels and obesity was also found in most subgroups through subgroup analysis.Conclusions Our study supports the negative association between serum vitamin E levels and overweight/obesity in ado-lescents.A higher serum vitamin E level may be associated with a reduced probability of obesity in girls,but not in boys.

关 键 词：Adolescent health Body mass index Z scores OBESITY OVERWEIGHT Vitamin E 

分 类 号：R725.8[医药卫生—儿科]